Ning Leng

6.6k citations

33 papers · 2.5k · 1 hit paper · h-index 20

Impact in

Cancer Research top 5%
- Cancer-related molecular mechanisms research
Molecular Biology top 5%
- Single-cell and spatial transcriptomics
- Gene expression and cancer classification
- Gene Regulatory Network Analysis
- Pluripotent Stem Cells Research
- RNA Research and Splicing
- RNA modifications and cancer
- Genomics and Phylogenetic Studies

Papers in

Molecular Biology 16
- Single-cell and spatial transcriptomics 6
- Pluripotent Stem Cells Research 3
- Epigenetics and DNA Methylation 3
Pulmonary and Respiratory Medicine 6
- Ferroptosis and cancer prognosis 3
- Renal cell carcinoma treatment 3

Co-authors: Christina Kendziorski (15 shared papers)James A. Thomson (13 shared papers)Ron Stewart (13 shared papers)Anna I. Rissman (3 shared papers)Jill D. Haag (3 shared papers)Bart M. G. Smits (3 shared papers)Michael N. Gould (3 shared papers)John A. Dawson (2 shared papers)
Journals: Bioinformatics (4 papers)Nature Communications (2 papers)PLoS Computational Biology (2 papers)Cancer Research (2 papers)PLoS ONE (2 papers)
Partner nations: United States France United Kingdom

In The Last Decade

Ning Leng

31 papers receiving 2.5k citations

Ning Leng's Hit Papers

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EBSeq: an empirical Bayes hierarchical model for inference in RNA-seq experiments 2013 · 979 citations

Peers

Countries citing papers authored by Ning Leng

Since Specialization

Citations

This map shows the geographic impact of Ning Leng's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ning Leng with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ning Leng more than expected).

Fields of papers citing papers by Ning Leng

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ning Leng. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ning Leng. The network helps show where Ning Leng may publish in the future.

Co-authors

The 25 scholars most cited alongside Ning Leng, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ning Leng Line = papers co-authored together Ning Leng links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 33 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	EBSeq: an empirical Bayes hierarchical model for inference in RNA-seq experiments Bioinformatics ·Ning Leng, John A. Dawson, James A. Thomson, Victor Ruotti, Anna I. Rissman, Bart M. G. Smits, Jill D. Haag, Michael N. Gould, Ron Stewart, Christina Kendziorski Hit paper breakdown →	2013	979
2	Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm Genome biology ·Li‐Fang Chu, Ning Leng, Jue Zhang, Zhonggang Hou, Daniel Mamott, David Vereide, Jeea Choi, Christina Kendziorski, Ron Stewart, James A. Thomson	2016	319
3	SCnorm: robust normalization of single-cell RNA-seq data Nature Methods ·Rhonda Bacher, Li‐Fang Chu, Ning Leng, Audrey P. Gasch, James A. Thomson, Ron Stewart, Michael A. Newton, Christina Kendziorski	2017	195
4	Oscope identifies oscillatory genes in unsynchronized single-cell RNA-seq experiments Nature Methods ·Ning Leng, Li‐Fang Chu, Christopher Barry, Yuan Li, Jeea Choi, Xiaomao Li, Peng Jiang, Ron Stewart, James A. Thomson, Christina Kendziorski	2015	122
5	Comparative RNA-seq Analysis in the Unsequenced Axolotl: The Oncogene Burst Highlights Early Gene Expression in the Blastema PLoS Computational Biology ·Ron Stewart, Cynthia Alexander Rascón, Shulan Tian, Jeff Nie, Christopher Barry, Li‐Fang Chu, Hamisha Ardalani, Ryan J. Wagner, Mitchell D. Probasco, Jennifer M. Bolin, Ning Leng, Srikumar Sengupta, Michael Volkmer, Bianca Habermann, Elly M. Tanaka, James A. Thomson, Colin N. Dewey	2013	110
6	Functional characterization of human pluripotent stem cell-derived arterial endothelial cells Proceedings of the National Academy of Sciences ·Jue Zhang, Li‐Fang Chu, Zhonggang Hou, Michael P. Schwartz, Timothy A. Hacker, Vernella Vickerman, Scott Swanson, Ning Leng, Bao Kim Nguyen, Angela L. Elwell, Jennifer M. Bolin, Matthew E. Brown, Ron Stewart, William J. Burlingham, William L. Murphy, James A. Thomson	2017	109
7	The Osteoblast to Osteocyte Transition: Epigenetic Changes and Response to the Vitamin D₃Hormone Molecular Endocrinology ·Hillary C. St. John, Kathleen A. Bishop, Mark B. Meyer, Nancy A. Benkusky, Ning Leng, Christina Kendziorski, Lynda F. Bonewald, J. Wesley Pike	2014	103
8	EBSeq-HMM: a Bayesian approach for identifying gene-expression changes in ordered RNA-seq experiments Bioinformatics ·Ning Leng, Yuan Li, Brian E. McIntosh, Bao Kim Nguyen, Bret Duffin, Shulan Tian, James A. Thomson, Colin N. Dewey, Ron Stewart, Christina Kendziorski	2015	72
9	Molecular correlates differentiate response to atezolizumab (atezo) + bevacizumab (bev) vs sunitinib (sun): Results from a phase III study (IMmotion151) in untreated metastatic renal cell carcinoma (mRCC) Annals of Oncology ·Brian I. Rini, Mahrukh Huseni, Michael B. Atkins, David F. McDermott, T.B. Powles, Bernard Escudier, Romain Banchereau, L.-F. Liu, Ning Leng, Junjie Fan, Jennifer Doss, Sam C. Nalle, Susheela Carroll, S. Li, Christina Schiff, M. Green, Robert J. Motzer	2018	61
10	EBSeq: an empirical Bayes hierarchical model for inference in RNA-seq experiments Bioinformatics ·Ning Leng, John A. Dawson, James A. Thomson, Victor Ruotti, Anna I. Rissman, Bart M. G. Smits, Jill D. Haag, Michael N. Gould, Ron Stewart, Christina Kendziorski	2013	58
11	A vehicle-based measurement framework for enhancing whitespace spectrum databases Tan Zhang, Ning Leng, Suman Banerjee	2014	54
12	Atezolizumab (atezo) vs. chemotherapy (chemo) in platinum-treated locally advanced or metastatic urothelial carcinoma (mUC): Immune biomarkers, tumor mutational burden (TMB), and clinical outcomes from the phase III IMvigor211 study. Journal of Clinical Oncology ·Thomas Powles, Yohann Loriot, Alain Ravaud, Nicholas J. Vogelzang, Ignacio Durán, Margitta Retz, Ugo De Giorgi, Stéphane Oudard, Aristotelis Bamias, Hartmut Koeppen, Ning Leng, Edward E. Kadel, Priti S. Hegde, Na Cui, Xiaodong Shen, Christina Louise Derleth, Marjorie C. Green, Romain Banchereau, Sanjeev Mariathasan, Michiel Simon Van Der Heijden	2018	35
13	Histone chaperone ASF1B promotes humanβ-cell proliferation via recruitment of histone H3.3 Cell Cycle ·Pradyut K. Paul, Mary E. Rabaglia, Chen‐Yu Wang, Donald S. Stapleton, Ning Leng, Christina Kendziorski, Peter W. Lewis, Mark P. Keller, Alan Attie	2016	34
14	A Wireless Spectrum Analyzer in Your Pocket Tan Zhang, Ashish Patro, Ning Leng, Suman Banerjee	2015	34
15	Trendy: segmented regression analysis of expression dynamics in high-throughput ordered profiling experiments BMC Bioinformatics ·Rhonda Bacher, Ning Leng, Li‐Fang Chu, Zijian Ni, James A. Thomson, Christina Kendziorski, Ron Stewart	2018	28
16	Collaborative rewiring of the pluripotency network by chromatin and signalling modulating pathways Nature Communications ·Khoa Tran, Steven A. Jackson, Zachariah P. G. Olufs, Nur Zafirah Zaidan, Ning Leng, Christina Kendziorski, Sushmita Roy, Rupa Sridharan	2015	26
17	Analysis of embryonic development in the unsequenced axolotl: Waves of transcriptomic upheaval and stability Developmental Biology ·Peng Jiang, Jeffrey D. Nelson, Ning Leng, Michael Collins, Scott Swanson, Colin N. Dewey, James A. Thomson, Ron Stewart	2016	22
18	Tumor, immune, and stromal characteristics associated with clinical outcomes with atezolizumab (atezo) + platinum-based chemotherapy (PBC) or atezo monotherapy (mono) versus PBC in metastatic urothelial cancer (mUC) from the phase III IMvigor130 study. Journal of Clinical Oncology ·Matt D. Galsky, Romain Banchereau, Habib Hamidi, Ning Leng, Will Harris, Peter H. O’Donnell, Edward E. Kadel, Kobe Yuen, Dexter X. Jin, Hartmut Koeppen, Darren Tayama, Enrique Grande, José Ángel Arranz, Maria De Santis, Ian D. Davis, Eiji Kikuchi, Xiaodong Shen, Aristotelis Bamias, Sanjeev Mariathasan	2020	20
19	The Gene Desert Mammary Carcinoma Susceptibility Locus Mcs1a Regulates Nr2f1 Modifying Mammary Epithelial Cell Differentiation and Proliferation PLoS Genetics ·Bart M. G. Smits, Jill D. Haag, Anna I. Rissman, Deepak Sharma, Ann Tran, Alexi A. Schoenborn, Rachael Baird, Dan S. Peiffer, David Q. Leinweber, Matthew J. Muelbl, Amanda L. Meilahn, Mark R. Eichelberg, Ning Leng, Christina Kendziorski, Manorama C. John, Patricia A. Powers, Caroline M. Alexander, Michael N. Gould	2013	19
20	Caseinomacropeptide modifies the heat-induced denaturation–aggregation process of β-lactoglobulin International Dairy Journal ·Thomas Croguennec, Ning Leng, Pascaline Hamon, Florence Rousseau, Romain Jeantet, Saı̈d Bouhallab	2014	19

About Ning Leng

Ning Leng is a scholar working on Molecular Biology, Pulmonary and Respiratory Medicine, Surgery, Oncology and Cancer Research, having authored 33 papers that have together received 2.5k indexed citations. Recurring topics across this work include Single-cell and spatial transcriptomics (6 papers), Cancer Immunotherapy and Biomarkers (4 papers), Ferroptosis and cancer prognosis (3 papers), Renal cell carcinoma treatment (3 papers), Pluripotent Stem Cells Research (3 papers), Bladder and Urothelial Cancer Treatments (3 papers), Epigenetics and DNA Methylation (3 papers) and Cancer Genomics and Diagnostics (2 papers). The work is most often cited by research in Cancer Research (359 citations), Molecular Biology (1.6k citations), Biophysics (90 citations), Immunology (177 citations) and Aging (15 citations). Ning Leng has collaborated with scholars based in United States, France and United Kingdom. Frequent co-authors include Christina Kendziorski, James A. Thomson, Ron Stewart, Anna I. Rissman, Jill D. Haag, Bart M. G. Smits, Michael N. Gould, John A. Dawson, Victor Ruotti and Li‐Fang Chu. Their work appears in journals such as Bioinformatics, Nature Communications, PLoS Computational Biology, Cancer Research and PLoS ONE.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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About Ning Leng

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