Nigel P.C. Walker

12.8k citations

100 papers · 10.0k · 1 hit paper · h-index 32

Impact in

Inorganic Chemistry top 0.2%
- Crystal structures of chemical compounds
- Synthesis and characterization of novel inorganic/organometallic compounds
- Asymmetric Hydrogenation and Catalysis
- Inorganic Chemistry and Materials
Organic Chemistry top 0.2%
- Organometallic Complex Synthesis and Catalysis
- Organometallic Compounds Synthesis and Characterization

Papers in

Organic Chemistry 41
- Organometallic Complex Synthesis and Catalysis 16
- Synthesis and biological activity 5
- Coordination Chemistry and Organometallics 5
Molecular Biology 32

Co-authors: David I. Stuart (7 shared papers)Zhulun Wang (20 shared papers)E. Yvonne Jones (4 shared papers)Haoda Xu (8 shared papers)Michael B. Hursthouse (25 shared papers)Jinsong Liu (8 shared papers)M. Lewis (2 shared papers)K. Ravi Acharya (2 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (13 papers)Journal of Biological Chemistry (5 papers)Journal of Medicinal Chemistry (4 papers)Inorganica Chimica Acta (3 papers)Polyhedron (3 papers)
Partner nations: United States United Kingdom Germany

In The Last Decade

Nigel P.C. Walker

97 papers receiving 9.0k citations

Nigel P.C. Walker's Hit Papers

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An empirical method for correcting diffractometer data for absorption effects 1983 · 5.7k citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1983 Acta Crystallographica Section A Foundations of Crystallography

Peers

Countries citing papers authored by Nigel P.C. Walker

Since Specialization

Citations

This map shows the geographic impact of Nigel P.C. Walker's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nigel P.C. Walker with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nigel P.C. Walker more than expected).

Fields of papers citing papers by Nigel P.C. Walker

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nigel P.C. Walker. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nigel P.C. Walker. The network helps show where Nigel P.C. Walker may publish in the future.

Co-authors

The 25 scholars most cited alongside Nigel P.C. Walker, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Nigel P.C. Walker Line = papers co-authored together Nigel P.C. Walker links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 100 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	An empirical method for correcting diffractometer data for absorption effects Acta Crystallographica Section A Foundations of Crystallography ·Nigel P.C. Walker, David I. Stuart Hit paper breakdown →	1983	5693
2	Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors Nature ·Zhulun Wang, G Benoît, Jinsong Liu, Srividya Prasad, Piia Aarnisalo, Xiaohong Liu, Haoda Xu, Nigel P.C. Walker, Thomas Perlmann	2003	468
3	Structure of tumour necrosis factor Nature ·E. Yvonne Jones, David I. Stuart, Nigel P.C. Walker	1989	419
4	Refined structure of baboon α-lactalbumin at 1.7 Å resolution Journal of Molecular Biology ·K. Ravi Acharya, David I. Stuart, Nigel P.C. Walker, M. Lewis, D.C. Phillips	1989	247
5	The Crystal Structure of PCSK9: A Regulator of Plasma LDL-Cholesterol Structure ·Derek E. Piper, Simon Jackson, Qiang Liu, William G. Romanow, Susan Shetterly, Stephen T. Thibault, Bei Shan, Nigel P.C. Walker	2007	205
6	Structure-Guided Design, Synthesis, and Evaluation of Guanine-Derived Inhibitors of the eIF4E mRNA–Cap Interaction Journal of Medicinal Chemistry ·Xiaoqi Chen, David J. Kopecky, Jeff Mihalic, Shawn Jeffries, Xiaoshan Min, Julie A. Heath, Jeff Deignan, Sujen Lai, Zice Fu, Cristiano R. W. Guimarães, Shanling Shen, Shyun Li, Sheree Johnstone, Stephen Thibault, Haoda Xu, Mario Cardozo, Shen Wang, Nigel P.C. Walker, Frank Kayser, Zhulun Wang	2012	194
7	α-Lactalbumin possesses a novel calcium binding loop Nature ·David I. Stuart, K. Ravi Acharya, Nigel P.C. Walker, Samuel G. Smith, M. Lewis, D.C. Phillips	1986	175
8	Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers Biochemical Journal ·Sylvia Herter, Derek E. Piper, Wade H. Aaron, Timothy Gabriele, Gene Cutler, Ping Cao, Ami S. Bhatt, Youngchool Choe, Charles S. Craik, Nigel P.C. Walker, David Meininger, Timothy Hoey, Richard J. Austin	2005	153
9	Molecular Basis of Sphingosine Kinase 1 Substrate Recognition and Catalysis Structure ·Zhulun Wang, Xiaoshan Min, Shou-Hua Xiao, Sheree Johnstone, William G. Romanow, David Meininger, Haoda Xu, Jinsong Liu, Jessica Dai, Songzhu An, Stephen Thibault, Nigel P.C. Walker	2013	147
10	Crystal Structures of IRAK-4 Kinase in Complex with Inhibitors: A Serine/Threonine Kinase with Tyrosine as a Gatekeeper Structure ·Zhulun Wang, Jinsong Liu, Athena Sudom, Merrill Ayres, Shyun Li, Holger Wesche, Jay P. Powers, Nigel P.C. Walker	2006	117
11	IRAK-4 Inhibitors for Inflammation Current Topics in Medicinal Chemistry ·Zhulun Wang, Holger Wesche, Tracey Stevens, Nigel P.C. Walker, Wen‐Chen Yeh	2009	115
12	SAR and Mode of Action of Novel Non-Nucleoside Inhibitors of Hepatitis C NS5b RNA Polymerase Journal of Medicinal Chemistry ·Jay P. Powers, Derek E. Piper, Yang Li, V. Mayorga, John V. Anzola, James Chen, Juan C. Jaén, Gary Lee, Jinqian Liu, M.G. Peterson, George Tonn, Qiuping Ye, Nigel P.C. Walker, Zhulun Wang	2006	112
13	INT131: A Selective Modulator of PPARγ Journal of Molecular Biology ·Alykhan Motani, Zhulun Wang, Jennifer Weiszmann, Lawrence R. McGee, Gary Lee, Qingxiang Liu, Jocelyn Staunton, Zexu Fang, Helen Fuentes, Michelle Lindström, Jinsong Liu, Donna H.T. Biermann, Juan C. Jaén, Nigel P.C. Walker, R. Marc Learned, Jinlong Chen, Yang Li	2009	100
14	Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4 Bioorganic & Medicinal Chemistry Letters ·Jay P. Powers, Shyun Li, Juan C. Jaén, Jinqian Liu, Nigel P.C. Walker, Zhulun Wang, Holger Wesche	2006	99
15	Refined structure of the acetazolamide complex of human carbonic anhydrase II at 1.9 Å International Journal of Biological Macromolecules ·Jukka Vidgren, Anders Liljas, Nigel P.C. Walker	1990	92
16	Discovery and Optimization of a Novel Class of Orally Active Nonpeptidic Endothelin-A Receptor Antagonists Journal of Medicinal Chemistry ·Hartmut Riechers, Hans-Peter Albrecht, Willi Amberg, Ernst A. Baumann, Harald Bernard, Hans‐Joachim Böhm, Dagmar Klinge, Andreas Kling, Stefan Müller, Manfred Raschack, Liliane Unger, Nigel P.C. Walker, Wolfgang Wernet	1996	91
17	Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2) Journal of Biological Chemistry ·Xiaoshan Min, Daniela Ungureanu, Sarah Sollid Maxwell, Henrik M. Hammarén, Steve Thibault, Ellin‐Kristina Hillert, Merrill Ayres, B. W. Greenfield, John Eksterowicz, Chris Gabel, Nigel P.C. Walker, Olli Silvennoinen, Zhulun Wang	2015	79
18	Identification and Characterization of a Non-retinoid Ligand for Retinol-binding Protein 4 Which Lowers Serum Retinol-binding Protein 4 Levels in Vivo Journal of Biological Chemistry ·Alykhan Motani, Zhulun Wang, Marion Conn, Karen Siegler, Ying Zhang, Qingxiang Liu, Sheree Johnstone, Haoda Xu, Steve Thibault, Yingcai Wang, Pingchen Fan, Richard Connors, Hoa Le, Guifen Xu, Nigel P.C. Walker, Bei Shan, Peter Coward	2009	69
19	T2384, a Novel Antidiabetic Agent with Unique Peroxisome Proliferator-activated Receptor γ Binding Properties Journal of Biological Chemistry ·Yang Li, Zhulun Wang, Noboru Furukawa, Patrick Escaron, Jennifer Weiszmann, Gary Lee, Michelle Lindström, Jinsong Liu, Xiaohong Liu, Haoda Xu, Olga Plotnikova, Vidya Prasad, Nigel P.C. Walker, R. Marc Learned, Jin Long Chen	2008	62
20	Synthesis and optimization of substituted furo[2,3-d]-pyrimidin-4-amines and 7H-pyrrolo[2,3-d]pyrimidin-4-amines as ACK1 inhibitors Bioorganic & Medicinal Chemistry Letters ·Xian‐Yun Jiao, David J. Kopecky, Jinsong Liu, Jinqian Liu, Juan C. Jaén, Mario Cardozo, Rajiv Sharma, Nigel P.C. Walker, Holger Wesche, Shyun Li, Ellyn Farrelly, Shou-Hua Xiao, Zhulun Wang, Frank Kayser	2012	58

About Nigel P.C. Walker

Nigel P.C. Walker is a scholar working on Organic Chemistry, Molecular Biology, Oncology, Inorganic Chemistry and Immunology, having authored 100 papers that have together received 10.0k indexed citations. Recurring topics across this work include Organometallic Complex Synthesis and Catalysis (16 papers), Metal complexes synthesis and properties (8 papers), Immune Response and Inflammation (7 papers), Cytokine Signaling Pathways and Interactions (6 papers), Synthesis and characterization of novel inorganic/organometallic compounds (6 papers), Monoclonal and Polyclonal Antibodies Research (5 papers), Synthesis and biological activity (5 papers) and Coordination Chemistry and Organometallics (5 papers). The work is most often cited by research in Inorganic Chemistry (3.5k citations), Organic Chemistry (4.4k citations), Oncology (2.2k citations), Electronic, Optical and Magnetic Materials (1.6k citations) and Process Chemistry and Technology (181 citations). Nigel P.C. Walker has collaborated with scholars based in United States, United Kingdom and Germany. Frequent co-authors include David I. Stuart, Zhulun Wang, E. Yvonne Jones, Haoda Xu, Michael B. Hursthouse, Jinsong Liu, M. Lewis, K. Ravi Acharya, D.C. Phillips and Holger Wesche. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Biological Chemistry, Journal of Medicinal Chemistry, Inorganica Chimica Acta and Polyhedron.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Nigel P.C. Walker

Nigel P.C. Walker's Hit Papers

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About Nigel P.C. Walker

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