Ming S. Chen

2.5k citations

28 papers · 2.2k · 1 hit paper · h-index 18

Impact in

Virology top 2%
- HIV Research and Treatment
Epidemiology top 2%
- Influenza Virus Research Studies
- Respiratory viral infections research
- Cytomegalovirus and herpesvirus research

Papers in

Molecular Biology 14
- DNA and Nucleic Acid Chemistry 5
- Biochemical and Molecular Research 5
Infectious Diseases 13
- HIV/AIDS drug development and treatment 13

Co-authors: Choung U. Kim (4 shared papers)Norbert Bischofberger (4 shared papers)Dirk B. Mendel (4 shared papers)Lijun Zhang (3 shared papers)Willard Lew (3 shared papers)William H. Prusoff (12 shared papers)Matthew A. Williams (2 shared papers)S. Swaminathan (2 shared papers)
Journals: Journal of Medicinal Chemistry (8 papers)Biochemical Pharmacology (6 papers)Antimicrobial Agents and Chemotherapy (2 papers)Biochemistry (2 papers)Methods in enzymology on CD-ROM/Methods in enzymology (2 papers)
Partner nations: United States Germany United Kingdom

In The Last Decade

Ming S. Chen

28 papers receiving 2.1k citations

Ming S. Chen's Hit Papers

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Influenza Neuraminidase Inhibitors Possessing a Novel Hydrophobic Interaction in the Enzyme Active Site: Design, Synthesis, and Structural Analysis of Carbocyclic Sialic Acid Analogues with Potent Anti-Influenza Activity 1997 · 947 citations

Peers

Countries citing papers authored by Ming S. Chen

Since Specialization

Citations

This map shows the geographic impact of Ming S. Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ming S. Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ming S. Chen more than expected).

Fields of papers citing papers by Ming S. Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ming S. Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ming S. Chen. The network helps show where Ming S. Chen may publish in the future.

Co-authors

The 25 scholars most cited alongside Ming S. Chen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ming S. Chen Line = papers co-authored together Ming S. Chen links everyone, so they are left out of the graph.

All Works

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#	Work
1	Influenza Neuraminidase Inhibitors Possessing a Novel Hydrophobic Interaction in the Enzyme Active Site: Design, Synthesis, and Structural Analysis of Carbocyclic Sialic Acid Analogues with Potent Anti-Influenza Activity Journal of the American Chemical Society ·Choung U. Kim, Willard Lew, Matthew A. Williams, Hongtao Liu, Lijun Zhang, S. Swaminathan, Norbert Bischofberger, Ming S. Chen, Dirk B. Mendel, Chun Y. Tai, W.G. Laver, Raymond C. Stevens Hit paper breakdown →	1997	947
2	Oral Administration of a Prodrug of the Influenza Virus Neuraminidase Inhibitor GS 4071 Protects Mice and Ferrets against Influenza Infection Antimicrobial Agents and Chemotherapy ·Dirk B. Mendel, Chun Y. Tai, Paul A. Escarpe, Weixing Li, Robert W. Sidwell, John H. Huffman, Clive Sweet, K. J. Jakeman, James Merson, Steven Lacy, Willard Lew, Matthew A. Williams, Lijun Zhang, Ming S. Chen, Norbert Bischofberger, Choung U. Kim	1998	231
3	Identification of GS 4104 as an Orally Bioavailable Prodrug of the Influenza Virus Neuraminidase Inhibitor GS 4071 Antimicrobial Agents and Chemotherapy ·Weixing Li, Paul A. Escarpe, Eugene Eisenberg, Kenneth C. Cundy, Clive Sweet, K. J. Jakeman, James Merson, Willard Lew, M.A. Williams, Lijun Zhang, Choung U. Kim, Norbert Bischofberger, Ming S. Chen, Dirk B. Mendel	1998	195
4	Synthesis and antiviral activity of various 3'-azido, 3'-amino, 2',3'-unsaturated, and 2',3'-dideoxy analogs of pyrimidine deoxyribonucleosides against retroviruses Journal of Medicinal Chemistry ·Tai Shun Lin, Ming S. Chen, C. McLaren, You Song Gao, Ismail Ghazzouli, William H. Prusoff	1987	114
5	Antiviral activity of 2′,3′-dideoxycytidin-2′-ene (2′,3′-dideoxy-2′,3′-didehydrocytidine) against human immunodeficiency virus in vitro Biochemical Pharmacology ·Tai‐Shun Lin, Raymond F. Sohinazi, Ming S. Chen, Elaine Kinney-Thomas, William H. Prusoff	1987	92
6	Kinetic analysis of the interaction of cidofovir diphosphate with human cytomegalovirus DNA polymerase Biochemical Pharmacology ·Xiaofeng Xiong, Jeffrey L. Smith, Choung Kim, Eng‐Shang Huang, Ming S. Chen	1996	71
7	Minor Groove DNA Binders as Antimicrobial Agents. 1. Pyrrole Tetraamides Are Potent Antibacterials against Vancomycin Resistant Enteroccoci and Methicillin Resistant Staphylococcus aureus Journal of Medicinal Chemistry ·Natalia Dyatkina, Christopher D. Roberts, Jesse Keicher, Yuqin Dai, Joshua P. Nadherny, Wentao Zhang, Uli Schmitz, Ana Kongpachith, Kevin Fung, А. А. Новиков, Lillian Lou, Mark Velligan, Alexander Khorlin, Ming S. Chen	2002	63
8	Kinetic analysis of the interaction between the diphosphate of (S)-1-(3-hydroxy-2-phosphonylemthoxypropyl)cytosine, ddCTP, AZTTP, and FIAUTP with human DNA polymerases β and γ Biochemical Pharmacology ·Julie M. Cherrington, S. J. W. Allen, Blaine H. McKee, Ming S. Chen	1994	60
9	New Series of Potent, Orally Bioavailable, Non-Peptidic Cyclic Sulfones as HIV-1 Protease Inhibitors Journal of Medicinal Chemistry ·Choung U. Kim, Lawrence R. McGee, Steven H. Krawczyk, Erik Harwood, Yoko Harada, S. Swaminathan, Norbert Bischofberger, Ming S. Chen, Julie M. Cherrington, Shelly Xiong, Linda C. Griffin, Kenneth C. Cundy, Angela Lee, Betty Yu, Sergli Gulnik, John W. Erickson	1996	59
10	Synthesis and biological activities of 5-(hydroxymethyl, azidomethyl, or aminomethyl)-2'-deoxyuridine and related 5'-substituted analogs Journal of Medicinal Chemistry ·George T. Shiau, Raymond F. Schinazi, Ming S. Chen, William H. Prusoff	1980	55
11	Antitumor Agents. 234. Design, Synthesis, and Biological Evaluation of Novel 4β-[(4‘ ‘-Benzamido)-Amino]-4‘-O-Demethyl-Epipodophyllotoxin Derivatives Journal of Medicinal Chemistry ·Zhiyan Xiao, Kenneth F. Bastow, John R. Vance, Robert S. Sidwell, Hui-Kang Wang, Ming S. Chen, Qian Shi, Kuo‐Hsiung Lee	2004	43
12	Inhibition of HIV reverse transcriptase by 2′,3′-dideoxynucleoside triphosphates Biochemical Pharmacology ·Ming S. Chen, Scott Oshana	1987	42
13	Selective action of 4'-azidothymidine triphosphate on reverse transcriptase of human immunodeficiency virus type 1 and human DNA polymerases .alpha. and .beta. Biochemistry ·Ming S. Chen, Rebecca T. Suttmann, Èva Papp, Paul D. Cannon, Mary J. McRoberts, Chinh Bach, William C. Copeland, Teresa S.‐F. Wang	1993	38
14	Antiviral iodinated pyrimidine deoxyribonucleosides: 5-iodo-2′-deoxyuridine; 5′-iodo-2′-deoxycytidine; 5-iodo-5′-amino-2′,5′-didoxyuridine Pharmacology & Therapeutics ·William H. Prusoff, Ming S. Chen, (unknown), Tai‐Shun Lin, George T. Shiau, Raymond F. Schinazi, Jamieson Walker	1979	35
15	The incorporation of 5-iodo-5′-amino-2′,5′-dideoxyuridine and 5-iodo-2′-deoxyuridine into herpes simplex virus DNA. Relationship between antiviral activity and effects on DNA structure Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis ·(unknown), Ming S. Chen, William H. Prusoff	1980	33
16	Antiviral and antineoplastic activities of pyrimidine arabinosyl nucleosides and their 5'-amino derivatives Journal of Medicinal Chemistry ·Raymond F. Schinazi, Ming S. Chen, William H. Prusoff	1979	29
17	1-(2-Deoxy-2-fluoro-.beta.-D-arabinofuranosyl)-5-ethyluracil. A highly selective antiherpes simplex agent Journal of Medicinal Chemistry ·Muzammil M. Mansuri, Ismail Ghazzouli, Ming S. Chen, Henry G. Howell, Paul R. Brodfuehrer, Daniel A. Benigni, John Martin	1987	28
18	[45] Thymidine kinase from Escherichia coli Methods in enzymology on CD-ROM/Methods in enzymology ·Ming S. Chen, William H. Prusoff	1978	18
19	Kinetic and photochemical studies and alteration of ultraviolet sensitivity of Escherichia coli thymidine kinase by halogenated allosteric regulators and substrate analogs Biochemistry ·Ming S. Chen, William H. Prusoff	1977	12
20	In vitro characterization of the anti-human cytomegalovirus activity of PMEA (Adefovir) Antiviral Research ·Xiao‐Feng Xiong, Carmina Flores, Michael D. Fuller, Dirk B. Mendel, Andrew Mulato, Keith Moon, Ming S. Chen, Julie M. Cherrington	1997	11

About Ming S. Chen

Ming S. Chen is a scholar working on Molecular Biology, Infectious Diseases, Organic Chemistry, Epidemiology and Virology, having authored 28 papers that have together received 2.2k indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (13 papers), Cytomegalovirus and herpesvirus research (5 papers), DNA and Nucleic Acid Chemistry (5 papers), HIV Research and Treatment (5 papers), Biochemical and Molecular Research (5 papers), Herpesvirus Infections and Treatments (4 papers), Influenza Virus Research Studies (3 papers) and Synthesis and Characterization of Heterocyclic Compounds (3 papers). The work is most often cited by research in Virology (234 citations), Epidemiology (1.1k citations), Infectious Diseases (455 citations), Organic Chemistry (730 citations) and Molecular Biology (1.0k citations). Ming S. Chen has collaborated with scholars based in United States, Germany and United Kingdom. Frequent co-authors include Choung U. Kim, Norbert Bischofberger, Dirk B. Mendel, Lijun Zhang, Willard Lew, William H. Prusoff, Matthew A. Williams, S. Swaminathan, Raymond C. Stevens and Hongtao Liu. Their work appears in journals such as Journal of Medicinal Chemistry, Biochemical Pharmacology, Antimicrobial Agents and Chemotherapy, Biochemistry and Methods in enzymology on CD-ROM/Methods in enzymology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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