Mark A. Graham

1.2k citations

27 papers · 1k · h-index 16

Impact in

Inorganic Chemistry top 5%
- Asymmetric Hydrogenation and Catalysis
Organic Chemistry top 5%
- Organoboron and organosilicon chemistry
- Synthesis and biological activity
- Asymmetric Synthesis and Catalysis
- Radical Photochemical Reactions

Papers in

Organic Chemistry 14
- Asymmetric Synthesis and Catalysis 6
- Radical Photochemical Reactions 3
- Synthesis and Catalytic Reactions 3
- Synthesis and biological activity 2
- Coordination Chemistry and Organometallics 2
Inorganic Chemistry 4
- Asymmetric Hydrogenation and Catalysis 4

Co-authors: Fung Kei Cheung (4 shared papers)Martin Wills (4 shared papers)David J. Fox (2 shared papers)Kathryn L. Chapman (1 shared paper)Nick Pullen (1 shared paper)Ian Ragan (1 shared paper)Guy J. Clarkson (2 shared papers)Matthew J. Hesse (1 shared paper)
Journals: Journal of Medicinal Chemistry (5 papers)Bioorganic & Medicinal Chemistry Letters (4 papers)Organic Process Research & Development (3 papers)Organic Letters (3 papers)Chemical Communications (2 papers)
Partner nations: United Kingdom China United States

In The Last Decade

Mark A. Graham

26 papers receiving 967 citations

Peers

Countries citing papers authored by Mark A. Graham

Since Specialization

Citations

This map shows the geographic impact of Mark A. Graham's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark A. Graham with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark A. Graham more than expected).

Fields of papers citing papers by Mark A. Graham

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark A. Graham. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark A. Graham. The network helps show where Mark A. Graham may publish in the future.

Co-authors

The 25 scholars most cited alongside Mark A. Graham, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Mark A. Graham Line = papers co-authored together Mark A. Graham links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 27 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	An Investigation into the Tether Length and Substitution Pattern of Arene-Substituted Complexes for Asymmetric Transfer Hydrogenation of Ketones Organic Letters ·Fung Kei Cheung, Changxue Lin, Franco Minissi, Adriana Lorente Crivillé, Mark A. Graham, David J. Fox, Martin Wills	2007	118
2	Enantioselective Rhodium(III)-Catalyzed Markovnikov Hydroboration of Unactivated Terminal Alkenes Journal of the American Chemical Society ·Beatrice S. L. Collins, Matthew J. Hesse, Mark A. Graham, Eddie L. Myers, Varinder Kumar Aggarwal +1 other	2017	116
3	Preclinical safety testing of monoclonal antibodies: the significance of species relevance Nature Reviews Drug Discovery ·Kathryn L. Chapman, Nick Pullen, Mark A. Graham, Ian Ragan	2007	89
4	Structure-Guided Design of Highly Selective and Potent Covalent Inhibitors of ERK1/2 Journal of Medicinal Chemistry ·Richard A. Ward, Nicola Colclough, Mairi Challinor, J.E. Debreczeni, Kay Eckersley, Gary Fairley, Lyman J. L. Feron, Vikki Flemington	2015	89
5	Optimization of a Series of Bivalent Triazolopyridazine Based Bromodomain and Extraterminal Inhibitors: The Discovery of (3R)-4-[2-[4-[1-(3-Methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-4-piperidyl]phenoxy]ethyl]-1,3-dimethyl-piperazin-2-one (AZD5153) Journal of Medicinal Chemistry ·Robert Hart Bradbury, Rowena J. Callis, Gregory R. Carr, Huawei Chen, Edwin A. Clark, Lyman J. L. Feron, Steve C. Glossop, Mark A. Graham	2016	80
6	The importance of the N–H bond in Ru/TsDPEN complexes for asymmetric transfer hydrogenation of ketones and imines Organic & Biomolecular Chemistry ·Rina Soni, Fung Kei Cheung, Guy J. Clarkson, José E. D. Martins, Mark A. Graham, Martin Wills	2011	78
7	Discovery of a Potent and Selective Oral Inhibitor of ERK1/2 (AZD0364) That Is Efficacious in Both Monotherapy and Combination Therapy in Models of Nonsmall Cell Lung Cancer (NSCLC) Journal of Medicinal Chemistry ·Richard A. Ward, Mark J. Anderton, Paul A. Bethel, Jason Breed, Calum Cook, Emma Jane Davies, Andrew P. Dobson, Zhiqiang Dong	2019	64
8	Kinetic and structural studies on ‘tethered’ Ru(ii) arene ketone reduction catalysts Dalton Transactions ·Fung Kei Cheung, Adam J. Clarke, Guy J. Clarkson, David J. Fox, Mark A. Graham, Changxue Lin, Adriana Lorente Crivillé, Martin Wills	2009	55
9	Development and Proof of Concept for a Large-Scale Photoredox Additive-Free Minisci Reaction Organic Process Research & Development ·Mark A. Graham, Gary M. Noonan, Janette H. Cherryman, James J. Douglas, Miguel Gonzalez, Lucinda V. Jackson, Kevin W. Leslie, Zhiqing Liu	2020	49
10	Structure-Guided Discovery of Potent and Selective Inhibitors of ERK1/2 from a Modestly Active and Promiscuous Chemical Start Point Journal of Medicinal Chemistry ·Richard A. Ward, Paul A. Bethel, Calum Cook, Emma Jane Davies, J.E. Debreczeni, Gary Fairley, Lyman J. L. Feron, Vikki Flemington	2017	44
11	The discovery of AZD5597, a potent imidazole pyrimidine amide CDK inhibitor suitable for intravenous dosing Bioorganic & Medicinal Chemistry Letters ·Clifford D. Jones, David M. Andrews, Andrew J Barker, Kevin Blades, Paula Daunt, Simon J. East, Catherine Geh, Mark A. Graham	2008	39
12	Tandem cationic cyclisation–aziridinium ion formation–nucleophilic ring opening: new methodology for the stereocontrolled synthesis of substituted pyrrolidines Chemical Communications ·Mark A. Graham, Mark A. Thornton-Pett, Christopher M. Rayner, Alan H. Wadsworth	2001	32
13	Imidazole piperazines: SAR and development of a potent class of cyclin-dependent kinase inhibitors with a novel binding mode Bioorganic & Medicinal Chemistry Letters ·M. Raymond V. Finlay, David G. Acton, David M. Andrews, Andrew J Barker, Michael Robert Dennis, Mark A. Graham, Clive P. Green, David W. Heaton	2008	29
14	Sulfonyl-morpholino-pyrimidines: SAR and development of a novel class of selective mTOR kinase inhibitor Bioorganic & Medicinal Chemistry Letters ·M. Raymond V. Finlay, David Buttar, Susan E. Critchlow, Allan P. Dishington, Shaun M. Fillery, Steve C. Glossop, Mark A. Graham, Trevor Johnson	2012	29
15	Discovery and Optimization of a Novel Series of Dyrk1B Kinase Inhibitors To Explore a MEK Resistance Hypothesis Journal of Medicinal Chemistry ·Jason G. Kettle, Peter G. Ballard, Catherine Bardelle, Mark J. Cockerill, Nicola Colclough, Susan E. Critchlow, J.E. Debreczeni, Gary Fairley	2015	28
16	Development and Scale-Up of an Improved Manufacturing Route to the ATR Inhibitor Ceralasertib Organic Process Research & Development ·Mark A. Graham, Hannah Askey, Andrew D. Campbell, Lai Chun Chan, Katie G. Cooper, Zhaoshan Cui, Gareth J. Ensor, Maria Rita Galan Espinosa	2020	26
17	“Ether-Linked” Organometallic Catalysts for Ketone Reduction Reactions Organometallics ·Fung Kei Cheung, Mark A. Graham, Franco Minissi, Martin Wills	2007	15
18	Synthesis of Functionalized Cyanopyrazoles via Magnesium Bases Organic Letters ·Allan P. Dishington, J. Lyman Feron, Kathryn Gill, Mark A. Graham, Ian Hollingsworth, Jennifer H. Pink, Andrew L. Roberts, Iain D. Simpson	2014	15
19	Studies on the Lewis acid mediated cleavage of α-aminoacetals: synthesis of novel 1,2-aminoethers, and evidence for α-alkoxy aziridinium ion intermediatesElectronic supplementary information (ESI) available: correlation of 1H NMR spectra between the syn and anti diastereomeric series. See http://www.rsc.org/suppdata/ob/b2/b210116e/ Organic & Biomolecular Chemistry ·Mark A. Graham, Alan H. Wadsworth, Abdul Zahid, Christopher M. Rayner	2003	9
20	Design and campaign synthesis of pyridine-based histone deacetylase inhibitors Bioorganic & Medicinal Chemistry Letters ·David M. Andrews, Keith M. Gibson, Mark A. Graham, Zbigniew S. Matusiak, Craig Roberts, Elaine S. E. Stokes, Madeleine C. Brady, Christine M. Chresta	2008	9

About Mark A. Graham

Mark A. Graham is a scholar working on Organic Chemistry, Inorganic Chemistry, Molecular Biology, Pharmaceutical Science and Small Animals, having authored 27 papers that have together received 1k indexed citations. Recurring topics across this work include Asymmetric Synthesis and Catalysis (6 papers), Asymmetric Hydrogenation and Catalysis (4 papers), Melanoma and MAPK Pathways (4 papers), Radical Photochemical Reactions (3 papers), Synthesis and Catalytic Reactions (3 papers), Histone Deacetylase Inhibitors Research (2 papers), Synthesis and biological activity (2 papers) and Coordination Chemistry and Organometallics (2 papers). The work is most often cited by research in Inorganic Chemistry (233 citations), Organic Chemistry (412 citations), Computational Theory and Mathematics (94 citations), Small Animals (34 citations) and Molecular Biology (219 citations). Mark A. Graham has collaborated with scholars based in United Kingdom, China and United States. Frequent co-authors include Fung Kei Cheung, Martin Wills, David J. Fox, Kathryn L. Chapman, Nick Pullen, Ian Ragan, Guy J. Clarkson, Matthew J. Hesse, Beatrice S. L. Collins and Varinder Kumar Aggarwal. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, Organic Process Research & Development, Organic Letters and Chemical Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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