Long Chen

5.4k citations

129 papers · 4.0k · h-index 34

Impact in

Health, Toxicology and Mutagenesis top 1%
- Heavy Metal Exposure and Toxicity
Nutrition and Dietetics top 1%
- Trace Elements in Health

Papers in

Molecular Biology 39
- PI3K/AKT/mTOR signaling in cancer 13
Epidemiology 25
- Autophagy in Disease and Therapy 14

Co-authors: Shile Huang (44 shared papers)Lei Liu (5 shared papers)Yan Luo (7 shared papers)Chong Xu (21 shared papers)Baoshan Xu (7 shared papers)Chunxiao Liu (17 shared papers)Lei Liu (4 shared papers)Xiuzhen Han (5 shared papers)
Journals: Journal of Neurochemistry (5 papers)Oncotarget (4 papers)Neuropharmacology (4 papers)Cellular Signalling (4 papers)Journal of Cellular Physiology (4 papers)
Partner nations: China United States India

In The Last Decade

Long Chen

127 papers receiving 3.9k citations

Peers

Countries citing papers authored by Long Chen

Since Specialization

Citations

This map shows the geographic impact of Long Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Long Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Long Chen more than expected).

Fields of papers citing papers by Long Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Long Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Long Chen. The network helps show where Long Chen may publish in the future.

Co-authors

The 25 scholars most cited alongside Long Chen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Long Chen Line = papers co-authored together Long Chen links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 129 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5 Free Radical Biology and Medicine ·Long Chen, Lei Liu, Shile Huang	2008	234
2	Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death Free Radical Biology and Medicine ·Long Chen, Baoshan Xu, Lei Liu, Yan Luo, Hongyu Zhou, Wenxing Chen, Tao Shen, Xiuzhen Han, Christopher D. Kontos, Shile Huang	2010	220
3	Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathway The International Journal of Biochemistry & Cell Biology ·Long Chen, Lei Liu, Jun Yin, Yan Luo, Shile Huang	2008	214
4	Calcium Signaling Is Involved in Cadmium-Induced Neuronal Apoptosis via Induction of Reactive Oxygen Species and Activation of MAPK/mTOR Network PLoS ONE ·Baoshan Xu, Sujuan Chen, Yan Luo, Zi Chen, Lei Liu, Hongyu Zhou, Wenxing Chen, Tao Shen, Xiuzhen Han, Long Chen, Shile Huang	2011	191
5	Curcumin Disrupts the Mammalian Target of Rapamycin-Raptor Complex Cancer Research ·Christopher S. Beevers, Long Chen, Lei Liu, Yan Luo, Nicholas J. G. Webster, Shile Huang	2009	167
6	Activation of AMPK and inactivation of Akt result in suppression of mTOR-mediated S6K1 and 4E-BP1 pathways leading to neuronal cell death in in vitro models of Parkinson's disease Cellular Signalling ·Yijiao Xu, Chunxiao Liu, Sujuan Chen, Yangjing Ye, Min Guo, Qian Ren, Lei Liu, Hai Zhang, Chong Xu, Qian Zhou, Shile Huang, Long Chen	2014	141
7	MAPK and mTOR pathways are involved in cadmium‐induced neuronal apoptosis Journal of Neurochemistry ·Long Chen, Lei Liu, Yan Luo, Shile Huang	2007	134
8	Advanced glycation end-products decreases expression of endothelial nitric oxide synthase through oxidative stress in human coronary artery endothelial cells Cardiovascular Diabetology ·Xiaomei Ren, Liqun Ren, Wei Qin, Hua Shao, Long Chen, Naifeng Liu	2017	131
9	Rapamycin Inhibits Cytoskeleton Reorganization and Cell Motility by Suppressing RhoA Expression and Activity Journal of Biological Chemistry ·Lei Liu, Yan Luo, Long Chen, Tao Shen, Baoshan Xu, Wenxing Chen, Hongyu Zhou, Xiuzhen Han, Shile Huang	2010	113
10	N‐acetyl‐L‐cysteine protects against cadmium‐induced neuronal apoptosis by inhibitingROS‐dependent activation ofAkt/mTORpathway in mouse brain Neuropathology and Applied Neurobiology ·Sujuan Chen, Qian Ren, Jinfei Zhang, Yangjing Ye, Zhen Zhang, Yijiao Xu, Min Guo, Haiyan Ji, Chong Xu, Chenjian Gu, Wei Gao, Shile Huang, Long Chen	2013	102
11	CaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell death Journal of Neurochemistry ·Sujuan Chen, Yijiao Xu, Baoshan Xu, Min Guo, Zhen Zhang, Lei Liu, Hongwei Ma, Zi Chen, Yan Luo, Shile Huang, Long Chen	2011	92
12	Circ_0078767 suppresses non‐small‐cell lung cancer by protecting RASSF1A expression via sponging miR‐330‐3p Cell Proliferation ·Ting Chen, Zuozhang Yang, Chao Liu, Li Wang, Jun Yang, Long Chen, (unknown)	2018	89
13	Rotenone Induction of Hydrogen Peroxide Inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E Pathways, Leading to Neuronal Apoptosis Toxicological Sciences ·Qian Zhou, Chunxiao Liu, Wen Liu, Hai Zhang, Ruijie Zhang, Jia Liu, Jinfei Zhang, Chong Xu, Lei Liu, Shile Huang, Long Chen	2014	88
14	C2 Region–Derived Peptides of β-Protein Kinase C Regulate Cardiac Ca²⁺Channels Circulation Research ·Zhi-Hao Zhang, John A. Johnson, Long Chen, Nabil El‐Sherif, Daria Mochly‐Rosen, Mohamed Boutjdir	1997	87
15	Enriched Selenium and Its Effects on Growth and Biochemical Composition in Lactobacillus bulgaricus Journal of Agricultural and Food Chemistry ·Shu Kai Xia, Long Chen, Jun Qing Liang	2007	71
16	Curcumin inhibits protein phosphatases 2A and 5, leading to activation of mitogen-activated protein kinases and death in tumor cells Carcinogenesis ·Xiuzhen Han, Baoshan Xu, Christopher S. Beevers, Yoshinobu Odaka, Long Chen, Lei Liu, Yan Luo, Hongyu Zhou, Wenxing Chen, Tao Shen, Shile Huang	2012	68
17	Protective effect of selenium-enriched lactobacillus on CCl₄-induced liver injury in mice and its possible mechanisms World Journal of Gastroenterology ·Long Chen	2005	66
18	Quercetin-induced apoptosis of HL-60 cells by reducing PI3K/Akt Molecular Biology Reports ·Yuan Zhang, Long Chen, (unknown), (unknown), (unknown), Chan Zou	2012	63
19	Rapamycin ameliorates cadmium-induced activation of MAPK pathway and neuronal apoptosis by preventing mitochondrial ROS inactivation of PP2A Neuropharmacology ·Chong Xu, Xiaoxue Wang, Yu Zhu, Xiaoqing Dong, Chunxiao Liu, Hai Zhang, Lei Liu, Shile Huang, Long Chen	2016	61
20	Cadmium results in accumulation of autophagosomes-dependent apoptosis through activating Akt-impaired autophagic flux in neuronal cells Cellular Signalling ·Hai Zhang, Xiaoqing Dong, Rui Zhao, Ruijie Zhang, Chong Xu, Xiaoxue Wang, Chunxiao Liu, Xiaoyu Hu, Shile Huang, Long Chen	2018	56

About Long Chen

Long Chen is a scholar working on Molecular Biology, Epidemiology, Immunology, Health, Toxicology and Mutagenesis and Neurology, having authored 129 papers that have together received 4.0k indexed citations. Recurring topics across this work include Heavy Metal Exposure and Toxicity (18 papers), Autophagy in Disease and Therapy (14 papers), PI3K/AKT/mTOR signaling in cancer (13 papers), Trace Elements in Health (9 papers), Immune Cell Function and Interaction (8 papers), Toxoplasma gondii Research Studies (6 papers), Parkinson's Disease Mechanisms and Treatments (6 papers) and Natural Compounds in Disease Treatment (4 papers). The work is most often cited by research in Health, Toxicology and Mutagenesis (764 citations), Nutrition and Dietetics (610 citations), Geriatrics and Gerontology (121 citations), Molecular Medicine (149 citations) and Complementary and alternative medicine (192 citations). Long Chen has collaborated with scholars based in China, United States and India. Frequent co-authors include Shile Huang, Lei Liu, Yan Luo, Chong Xu, Baoshan Xu, Chunxiao Liu, Lei Liu, Xiuzhen Han, Tao Shen and Yan Luo. Their work appears in journals such as Journal of Neurochemistry, Oncotarget, Neuropharmacology, Cellular Signalling and Journal of Cellular Physiology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Long Chen

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About Long Chen

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