John E. Arrowsmith

4.9k citations
18 papers · 3.7k · 5 hit papers · h-index 13

Impact in

Papers in

John E. Arrowsmith

18 papers receiving 3.5k citations

John E. Arrowsmith's Hit Papers

An analysis of the attrition of drug candidates from four major pharmaceutical companies 2015 · 1.1k citations
1.1k0+5+10Years since publication2505007501000

Peers

John E. Arrowsmith
Comparison fields: 5 of 155
  • Computational Theory and Mathematics 917
  • Pharmacology 412
  • Small Animals 149
  • Molecular Biology 1.4k
  • Statistics and Probability 162
Replace Christopher T. Dunwiddie with:
Christopher T. Dunwiddie United States
Jacques Hamon Switzerland
Paul Morgan United Kingdom
Aaron L. Schacht United States
Manuel Pastor Spain
Christine Brideau Canada
Daniel S. Mytelka United States
Adam Yasgar United States
David Cavalla United States
Dejan Bojanic United States
John E. Arrowsmith relative to Christopher T. Dunwiddie United States Christopher T. Dunwiddie's profile →
Citations per field
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Citations per year

Countries citing papers authored by John E. Arrowsmith

Since Specialization
Citations

This map shows the geographic impact of John E. Arrowsmith's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John E. Arrowsmith with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John E. Arrowsmith more than expected).

Fields of papers citing papers by John E. Arrowsmith

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John E. Arrowsmith. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John E. Arrowsmith. The network helps show where John E. Arrowsmith may publish in the future.

Co-authors

The 25 scholars most cited alongside John E. Arrowsmith, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John E. Arrowsmith Line = papers co-authored together John E. Arrowsmith links everyone, so they are left out of the graph.

All Works

18 of 18 papers shown
#Work
1
An analysis of the attrition of drug candidates from four major pharmaceutical companies
Hit paper breakdown →
20151113
2
Can the flow of medicines be improved? Fundamental pharmacokinetic and pharmacological principles toward improving Phase II survival
Hit paper breakdown →
2011553
3
Phase II and Phase III attrition rates 2011–2012
Hit paper breakdown →
2013547
4
Phase II failures: 2008–2010
Hit paper breakdown →
2011498
5
Phase III and submission failures: 2007–2010
Hit paper breakdown →
2011369
6 1986196
7 1990174
8 2012131
9 199049
10 197826
11 199125
12 198917
13 197914
14 19839
15 19807
16 19825
17 19823
18
A comprehensive analysis of development attrition in drug candidates from four major pharmaceutical companies
20151

About John E. Arrowsmith

John E. Arrowsmith is a scholar working on Organic Chemistry, Computational Theory and Mathematics, Economics and Econometrics, Cardiology and Cardiovascular Medicine and Virology, having authored 18 papers that have together received 3.7k indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (3 papers), Pharmaceutical Economics and Policy (3 papers), Synthesis of heterocyclic compounds (3 papers), Cardiac electrophysiology and arrhythmias (2 papers), Chemical Reaction Mechanisms (2 papers), Structural and Chemical Analysis of Organic and Inorganic Compounds (2 papers), Phenothiazines and Benzothiazines Synthesis and Activities (2 papers) and Pharmaceutical Quality and Counterfeiting (2 papers). The work is most often cited by research in Computational Theory and Mathematics (917 citations), Pharmacology (412 citations), Small Animals (149 citations), Molecular Biology (1.4k citations) and Statistics and Probability (162 citations). John E. Arrowsmith has collaborated with scholars based in United Kingdom and United States. Frequent co-authors include J. Philip Miller, William D. Pennie, Owen B. Wallace, Andrew R. Leach, Stephen D. Pickett, Alex. M. Weir, Garry Pairaudeau, Ji‐Bo Wang, Robert M. Owen and Michael J. Waring. Their work appears in journals such as Nature Reviews Drug Discovery, Journal of the Chemical Society Perkin Transactions 1, Journal of Medicinal Chemistry, Drug Discovery Today and Tetrahedron Letters.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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