Jay D. Horton

124 papers receiving 38.6k citations

Jay D. Horton's Hit Papers

DGAT2 inhibition blocks SREBP-1 cleavage and improves hepatic steatosis by increasing phosphatidylethanolamine in the ER 2024 · 60 citations
600+7+14Years since publication10002.0k3.0k

Peers

Jay D. Horton
Comparison fields: 5 of 157
  • Biochemistry 5.0k
  • Endocrinology, Diabetes and Metabolism 6.4k
  • Surgery 15.8k
  • Cancer Research 5.3k
  • Epidemiology 10.5k
Replace Helen H. Hobbs with:
Helen H. Hobbs United States
Jonathan C. Cohen United States
Timothy M. Willson United States
Peter Tontonoz United States
Steven A. Kliewer United States
Hitoshi Shimano Japan
Alan R. Tall United States
Jean‐Charles Fruchart France
Kristina Schoonjans Switzerland
James K. Liao United States
Jay D. Horton relative to Helen H. Hobbs United States Helen H. Hobbs's profile →
Citations per field
00.5×1.5×1.9×
Helen H. Hobbs · 1×
Citations per year

Countries citing papers authored by Jay D. Horton

Since Specialization
Citations

This map shows the geographic impact of Jay D. Horton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jay D. Horton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jay D. Horton more than expected).

Fields of papers citing papers by Jay D. Horton

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jay D. Horton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jay D. Horton. The network helps show where Jay D. Horton may publish in the future.

Co-authors

The 25 scholars most cited alongside Jay D. Horton, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jay D. Horton Line = papers co-authored together Jay D. Horton links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 125 papers — load more, or switch the sort, to bring in the rest.

#Work
1
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
Hit paper breakdown →
20023785
2
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
Hit paper breakdown →
20023624
3
Prevalence of Hepatic Steatosis in An Urban Population in the United States: Impact of Ethnicity
Hit paper breakdown →
20043007
4
Human Fatty Liver Disease: Old Questions and New Insights
Hit paper breakdown →
20111743
5
Molecular mediators of hepatic steatosis and liver injury
Hit paper breakdown →
20041607
6
Molecular mediators of hepatic steatosis and liver injury
Hit paper breakdown →
20041590
7
Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes
Hit paper breakdown →
20031197
8
Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells.
Hit paper breakdown →
1997736
9
Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a.
Hit paper breakdown →
1996725
10
Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells.
Hit paper breakdown →
1997675
11
Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes
Hit paper breakdown →
1999669
12
Binding of Proprotein Convertase Subtilisin/Kexin Type 9 to Epidermal Growth Factor-like Repeat A of Low Density Lipoprotein Receptor Decreases Receptor Recycling and Increases Degradation
Hit paper breakdown →
2007664
13
Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis
Hit paper breakdown →
2004635
14
Increased Levels of Nuclear SREBP-1c Associated with Fatty Livers in Two Mouse Models of Diabetes Mellitus
Hit paper breakdown →
1999617
15
A Highly Durable RNAi Therapeutic Inhibitor of PCSK9
Hit paper breakdown →
2016610
16
Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.
Hit paper breakdown →
1998609
17
Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9
Hit paper breakdown →
2005583
18
Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice
Hit paper breakdown →
1998582
19
Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol
Hit paper breakdown →
2002572
20
Diminished Hepatic Response to Fasting/Refeeding and Liver X Receptor Agonists in Mice with Selective Deficiency of Sterol Regulatory Element-binding Protein-1c
Hit paper breakdown →
2002571

About Jay D. Horton

Jay D. Horton is a scholar working on Surgery, Molecular Biology, Biochemistry, Endocrinology, Diabetes and Metabolism and Epidemiology, having authored 125 papers that have together received 39.5k indexed citations. Recurring topics across this work include Cholesterol and Lipid Metabolism (56 papers), Lipid metabolism and biosynthesis (40 papers), Peroxisome Proliferator-Activated Receptors (31 papers), Lipoproteins and Cardiovascular Health (19 papers), Liver Disease Diagnosis and Treatment (16 papers), Drug Transport and Resistance Mechanisms (15 papers), Adipose Tissue and Metabolism (14 papers) and Diet, Metabolism, and Disease (13 papers). The work is most often cited by research in Biochemistry (5.0k citations), Endocrinology, Diabetes and Metabolism (6.4k citations), Surgery (15.8k citations), Cancer Research (5.3k citations) and Epidemiology (10.5k citations). Jay D. Horton has collaborated with scholars based in United States, Poland and United Kingdom. Frequent co-authors include Joseph L. Goldstein, Michael S. Brown, Jeffrey D. Browning, Jonathan C. Cohen, Helen H. Hobbs, Iichiro Shimomura, Robert E. Hammer, Hitoshi Shimano, Yuriy K. Bashmakov and Young-Ah Moon. Their work appears in journals such as Journal of Clinical Investigation, Journal of Biological Chemistry, Journal of Lipid Research, Proceedings of the National Academy of Sciences and Cell Metabolism.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact