Jan Osinga

2.8k citations

40 papers · 2.2k · h-index 26

Impact in

Cancer Research top 5%
- Cancer Genomics and Diagnostics
Genetics top 5%
- Digestive system and related health

Papers in

Molecular Biology 21
- RNA modifications and cancer 5
- Epigenetics and DNA Methylation 4
Surgery 13
- Congenital gastrointestinal and neural anomalies 12

Co-authors: Charles H.C.M. Buys (21 shared papers)Robert M.W. Hofstra (22 shared papers)Klaas Kok (8 shared papers)Carel Meijers (4 shared papers)Harry Hollema (3 shared papers)Anneke Y. van der Veen (5 shared papers)Annemarie H. van der Hout (4 shared papers)B. Carritt (3 shared papers)
Journals: The American Journal of Human Genetics (3 papers)Human Genetics (3 papers)Genes Chromosomes and Cancer (3 papers)Gastroenterology (2 papers)Experimental Cell Research (2 papers)
Partner nations: Netherlands United States United Kingdom

In The Last Decade

Jan Osinga

40 papers receiving 2.1k citations

Peers

Countries citing papers authored by Jan Osinga

Since Specialization

Citations

This map shows the geographic impact of Jan Osinga's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jan Osinga with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jan Osinga more than expected).

Fields of papers citing papers by Jan Osinga

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jan Osinga. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jan Osinga. The network helps show where Jan Osinga may publish in the future.

Co-authors

The 25 scholars most cited alongside Jan Osinga, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jan Osinga Line = papers co-authored together Jan Osinga links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 40 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Deletion of a DNA sequence at the chromosomal region 3p21 in all major types of lung cancer Nature ·Klaas Kok, Jan Osinga, B. Carritt, Mary B. Davis, Annemarie H. van der Hout, Anneke Y. van der Veen, Rudy M. Landsvater, Lou F. M. H. de Leij, Henk H. Berendsen, Pieter E. Postmus, Sibrand Poppema, Charles H.C.M. Buys	1987	370
2	A homozygous mutation in the endothelin-3 gene associated with a combined Waardenburg type 2 and Hirschsprung phenotype (Shah-Waardenburg syndrome) Nature Genetics ·Robert M.W. Hofstra, Jan Osinga, Gita Tan-Sindhunata, Ying Wu, Erik-J. Kamsteeg, Rein P. Stulp, Conny M.A. van Ravenswaaij‐Arts, Daniëlle Majoor‐Krakauer, Misha Angrist, Aravinda Chakravarti, Carel Meijers, Charles H.C.M. Buys	1996	253
3	Histone Methyltransferase Gene SETD2 Is a Novel Tumor Suppressor Gene in Clear Cell Renal Cell Carcinoma Cancer Research ·Gerben Duns, (unknown), Inge van Duivenbode, Jan Osinga, Harry Hollema, Robert M.W. Hofstra, Klaas Kok	2010	198
4	Homozygous Nonsense Mutations in KIAA1279 Are Associated with Malformations of the Central and Enteric Nervous Systems The American Journal of Human Genetics ·Alice S. Brooks, Aida M. Bertoli‐Avella, Grzegorz Burzynski, Guido J. Breedveld, Jan Osinga, Ludolf G. Boven, Jane A. Hurst, Grazia M.S. Mancini, Maarten H. Lequin, I.F.M. de Coo, Ivana Matera, Esther de Graaff, Carel Meijers, Patrick J. Willems, Dick Tibboel, Ben A. Oostra, Robert M.W. Hofstra	2005	123
5	MSH2 andMLH1 mutations in sporadic replication error-positive colorectal carcinoma as assessed by two-dimensional DNA electrophoresis Genes Chromosomes and Cancer ·Ying Wu, Minna Nyström, Jan Osinga, Maaike W.G. Looman, Païvi Peltomäki, Lauri A. Aaltonen, Albert de la Chapelle, Robert M.W. Hofstra, Charles H.C.M. Buys	1997	105
6	Abundance of protein-bound sulfhydryl and bisulfide groups at chromosomal nucleolus organizing regions Chromosoma ·Charles H.C.M. Buys, Jan Osinga	1980	102
7	RET-Familial Medullary Thyroid Carcinoma Mutants Y791F and S891A Activate a Src/JAK/STAT3 Pathway, Independent of Glial Cell Line–Derived Neurotrophic Factor Cancer Research ·Iván Plaza-Menacho, Roelof Koster, Almer M. van der Sloot, Wim J. Quax, Jan Osinga, Tineke van der Sluis, Harry Hollema, Grzegorz Burzynski, Oliver Gimm, Charles H.C.M. Buys, Bart J. L. Eggen, Robert M.W. Hofstra	2005	76
8	RET andGDNF gene scanning in Hirschsprung patients using two dual denaturing gel systems Human Mutation ·Robert M.W. Hofstra, Ying Wu, Rein P. Stulp, Peter Elfferich, Jan Osinga, Saskia M Maas, Liesbeth Siderius, A S Brooks, Jenneke J. vd Ende, Vera M. R. Heydendael, Ren� S.V.M. Severijnen, Klaas M.A. Bax, Carel Meijers, C.H.C.M. Buys	2000	75
9	Severe Myocardial Fibrosis Caused by a Deletion of the 5’ End of the Lamin A/C Gene Journal of the American College of Cardiology ·J. Peter van Tintelen, René A. Tio, Wilhelmina S. Kerstjens‐Frederikse, Jop H. van Berlo, Ludolf G. Boven, Albert J.H. Suurmeijer, Stefan J. White, Johan T. den Dunnen, Gerard J. te Meerman, Yvonne J. Vos, Annemarie H. van der Hout, Jan Osinga, Maarten P. van den Berg, Dirk J. van Veldhuisen, Charles H.C.M. Buys, Robert M.W. Hofstra, Yigal M. Pinto	2007	73
10	The Effects of Four Different Tyrosine Kinase Inhibitors on Medullary and Papillary Thyroid Cancer Cells The Journal of Clinical Endocrinology & Metabolism ·Hans H G Verbeek, Maria M. Alves, Jan‐Willem B. de Groot, Jan Osinga, John Th. M. Plukker, Thera P. Links, Robert M.W. Hofstra	2011	71
11	Targeted exome sequencing in clear cell renal cell carcinoma tumors suggests aberrant chromatin regulation as a crucial step in ccRCC development Human Mutation ·Gerben Duns, Robert M.W. Hofstra, Jantine Sietzema, Harry Hollema, Inge van Duivenbode, Angela Kuik, Cor Giezen, Jan Osinga, Jelkje J. Bergsma, Harrie Bijnen, Pieter van der Vlies, Eva van den Berg, Klaas Kok	2012	63
12	Selective staining of the same set of nucleolar phosphoproteins by silver and Giemsa Chromosoma ·Charles H.C.M. Buys, Jan Osinga	1984	60
13	Mutations in Hirschsprung Disease: When Does a Mutation Contribute to the Phenotype European Journal of Human Genetics ·Robert M.W. Hofstra, Jan Osinga, Charles H.C.M. Buys	1997	53
14	A consanguineous family with Hirschsprung disease, microcephaly, and mental retardation (Goldberg-Shprintzen syndrome) Journal of Medical Genetics ·AS Brooks, M.H. Breuning, Jan Osinga, J.J. Vd Smagt, C E Catsman, (unknown), Carel Meijers, Robert M.W. Hofstra	1999	49
15	Identifying Candidate Hirschsprung Disease–Associated RET Variants The American Journal of Human Genetics ·Grzegorz Burzynski, Ilja M. Nolte, Agnes Bronda, Krista K. Bos, Jan Osinga, Iván Plaza-Menacho, Bas Twigt, Saskia M. Maas, Alice S. Brooks, B.G.M. Joke Verheij, H.C.M. Charles Buys, Robert M.W. Hofstra	2005	48
16	ABCD syndrome is caused by a homozygous mutation in the EDNRB gene American Journal of Medical Genetics ·(unknown), Jürgen Kunze, Jan Osinga, Anthonie J. van Essen, Robert M.W. Hofstra	2002	39
17	Localizing a putative mutation as the major contributor to the development of sporadic Hirschsprung disease to the RET genomic sequence between the promoter region and exon 2 European Journal of Human Genetics ·Grzegorz Burzynski, Ilja M. Nolte, Jan Osinga, Isabella Ceccherini, Bas Twigt, Saskia M. Maas, Alice Brooks, (unknown), Iván Plaza-Menacho, Charles H.C.M. Buys, Robert M.W. Hofstra	2004	38
18	KBP interacts with SCG10, linking Goldberg–Shprintzen syndrome to microtubule dynamics and neuronal differentiation Human Molecular Genetics ·Maria M. Alves, Grzegorz Burzynski, Jean‐Marie Delalande, Jan Osinga, Annemieke van der Goot, Amalia M. Dolga, Esther de Graaff, Alice S. Brooks, Marco Metzger, Ulrich Eisel, Iain T. Shepherd, Bart J. L. Eggen, Robert M.W. Hofstra	2010	35
19	A Rare Haplotype of the RET Proto-Oncogene Is a Risk-Modifying Allele in Hirschsprung Disease The American Journal of Human Genetics ·Paola Griseri, Bárbara Pesce, Giovanna Patrone, Jan Osinga, Francesca Puppo, Monica Sancandi, Robert M.W. Hofstra, G. Cara Romeo, Roberto Ravazzolo, Marcella Devoto, Isabella Ceccherini	2002	33
20	Variants in RET Associated With Hirschsprung's Disease Affect Binding of Transcription Factors and Gene Expression Gastroenterology ·Yunia Sribudiani, Marco Metzger, Jan Osinga, Amanda Rey, Alan J. Burns, Nikhil Thapar, Robert M.W. Hofstra	2010	33

About Jan Osinga

Jan Osinga is a scholar working on Molecular Biology, Surgery, Oncology, Genetics and Cancer Research, having authored 40 papers that have together received 2.2k indexed citations. Recurring topics across this work include Congenital gastrointestinal and neural anomalies (12 papers), RNA modifications and cancer (5 papers), Cancer Genomics and Diagnostics (4 papers), Lung Cancer Research Studies (4 papers), Epigenetics and DNA Methylation (4 papers), Neurogenetic and Muscular Disorders Research (4 papers), Digestive system and related health (4 papers) and Renal cell carcinoma treatment (3 papers). The work is most often cited by research in Cancer Research (371 citations), Genetics (445 citations), Surgery (634 citations), Molecular Biology (1.1k citations) and Pathology and Forensic Medicine (235 citations). Jan Osinga has collaborated with scholars based in Netherlands, United States and United Kingdom. Frequent co-authors include Charles H.C.M. Buys, Robert M.W. Hofstra, Klaas Kok, Carel Meijers, Harry Hollema, Anneke Y. van der Veen, Annemarie H. van der Hout, B. Carritt, Pieter E. Postmus and Lou F. M. H. de Leij. Their work appears in journals such as The American Journal of Human Genetics, Human Genetics, Genes Chromosomes and Cancer, Gastroenterology and Experimental Cell Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Jan Osinga

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Jan Osinga

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