Jacqui E. Hoffman

13 papers receiving 950 citations

Jacqui E. Hoffman's Hit Papers

Discovery of (10 R )-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro- 2H -8,4-(metheno)pyrazolo[4,3- h ][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations 2014 · 493 citations
4930+4+8Years since publication100200300400

Peers

Jacqui E. Hoffman
Comparison fields: 5 of 62
  • Pulmonary and Respiratory Medicine 371
  • Oncology 302
  • Organic Chemistry 254
  • Molecular Biology 555
  • Genetics 57
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Countries citing papers authored by Jacqui E. Hoffman

Since Specialization
Citations

This map shows the geographic impact of Jacqui E. Hoffman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jacqui E. Hoffman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jacqui E. Hoffman more than expected).

Fields of papers citing papers by Jacqui E. Hoffman

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jacqui E. Hoffman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jacqui E. Hoffman. The network helps show where Jacqui E. Hoffman may publish in the future.

Co-authors

The 25 scholars most cited alongside Jacqui E. Hoffman, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jacqui E. Hoffman Line = papers co-authored together Jacqui E. Hoffman links everyone, so they are left out of the graph.

All Works

13 of 13 papers shown
#Work
1
Discovery of (10 R )-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro- 2H -8,4-(metheno)pyrazolo[4,3- h ][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations
Hit paper breakdown →
2014493
2 2014105
3 201296
4 201069
5 201268
6 201040
7 202333
8 201030
9 201325
10 201820
11 201310
12 20091
13 20221

About Jacqui E. Hoffman

Jacqui E. Hoffman is a scholar working on Molecular Biology, Pharmacology, Organic Chemistry, Pulmonary and Respiratory Medicine and Endocrinology, Diabetes and Metabolism, having authored 13 papers that have together received 991 indexed citations. Recurring topics across this work include PI3K/AKT/mTOR signaling in cancer (5 papers), Lung Cancer Treatments and Mutations (3 papers), Cancer therapeutics and mechanisms (3 papers), Cancer Mechanisms and Therapy (2 papers), Quinazolinone synthesis and applications (2 papers), Lung Cancer Research Studies (2 papers), Biochemical and Molecular Research (2 papers) and Hormonal Regulation and Hypertension (2 papers). The work is most often cited by research in Pulmonary and Respiratory Medicine (371 citations), Oncology (302 citations), Organic Chemistry (254 citations), Molecular Biology (555 citations) and Genetics (57 citations). Jacqui E. Hoffman has collaborated with scholars based in United States and China. Frequent co-authors include Hengmiao Cheng, Simon R. Bailey, Matthew A. Marx, Daniel R. Knighton, Shubha Bagrodia, Eric Zhang, Shaoxian Sun, Robert S. Kania, Sacha Ninkovic and Qiyue Hu. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, MedChemComm, ACS Medicinal Chemistry Letters and Organic Process Research & Development.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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