Jaap Twisk

3.6k citations
49 papers · 2.9k · h-index 27

Impact in

Papers in

  • Genetics 20
    • Virus-based gene therapy research 12
    • Diabetes and associated disorders 11
  • Surgery 17
    • Cholesterol and Lipid Metabolism 15
Co-authors
Theo J.C. van Berkel (6 shared papers)Miranda Van Eck (5 shared papers)Diane Brisson (5 shared papers)Daniel Gaudet (5 shared papers)I. Sophie T. Bos (2 shared papers)Julie Méthot (4 shared papers)Jan Albert Kuivenhoven (13 shared papers)J. de Wal (4 shared papers)
Journals
Human Gene Therapy (8 papers)Biochemical Journal (4 papers)Arteriosclerosis Thrombosis and Vascular Biology (3 papers)Gene (2 papers)Journal of Lipid Research (2 papers)
Partner nations
NetherlandsCanadaUnited States

In The Last Decade

Jaap Twisk

49 papers receiving 2.9k citations

Peers

Jaap Twisk
Comparison fields: 5 of 94
  • Genetics 824
  • Endocrinology, Diabetes and Metabolism 416
  • Oncology 651
  • Surgery 1.0k
  • Cardiology and Cardiovascular Medicine 487
Replace Martine I. Darville with:
Martine I. Darville Belgium
Alessandro Cama Italy
Phoebe E. Fielding United States
S K Karathanasis United States
Damien C. Wilpitz United States
Runpei Wu United States
Yasuhiro Mitsuuchi United States
Sally P.A. McCormick New Zealand
Jeff L. Ellsworth United States
Lawrence S. Argetsinger United States
Jaap Twisk relative to Martine I. Darville Belgium Martine I. Darville's profile →
Citations per field
00.5×2×4×6×8×
Martine I. Darville · 1×
Citations per year

Countries citing papers authored by Jaap Twisk

Since Specialization
Citations

This map shows the geographic impact of Jaap Twisk's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jaap Twisk with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jaap Twisk more than expected).

Fields of papers citing papers by Jaap Twisk

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jaap Twisk. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jaap Twisk. The network helps show where Jaap Twisk may publish in the future.

Co-authors

The 25 scholars most cited alongside Jaap Twisk, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jaap Twisk Line = papers co-authored together Jaap Twisk links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 49 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Efficacy and long-term safety of alipogene tiparvovec (AAV1-LPLS447X) gene therapy for lipoprotein lipase deficiency: an open-label trial
Gene Therapy ·Daniel Gaudet, Julie Méthot, S. Déry, Diane Brisson, C Essiembre, G Tremblay, Karine Tremblay, J. de Wal, Jaap Twisk, N. van den Bulk, Valerie Sier-Ferreira, S van Deventer
2012308
2
Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues
Proceedings of the National Academy of Sciences ·Miranda Van Eck, I. Sophie T. Bos, Wolfgang E. Kaminski, Evelyn Orsó, G. Rothe, Jaap Twisk, Alfred Böttcher, Edwin S. van Amersfoort, Trudy A. Christiansen-Weber, Wai‐Ping Fung‐Leung, Theo J.C. van Berkel, Gerd Schmitz
2002303
3
The role of the LDL receptor in apolipoprotein B secretion
Journal of Clinical Investigation ·Jaap Twisk, Donald L. Gillian‐Daniel, Angie Tebon, Lin Wang, P. Hugh R. Barrett, Alan Attie
2000202
4
Differential Effects of Scavenger Receptor BI Deficiency on Lipid Metabolism in Cells of the Arterial Wall and in the Liver
Journal of Biological Chemistry ·Miranda Van Eck, Jaap Twisk, Menno Hoekstra, Brechje T. Van Rij, Christian A.C. van der Lans, I. Sophie T. Bos, J. Kar Kruijt, Folkert Kuipers, Theo J.C. van Berkel
2003198
5
Intramuscular Administration of AAV1-Lipoprotein Lipase S447X Lowers Triglycerides in Lipoprotein Lipase–Deficient Patients
Arteriosclerosis Thrombosis and Vascular Biology ·Erik S.G. Stroes, Melchior C. Nierman, J. J. M. Meulenberg, Remco Franssen, Jaap Twisk, C. P. Henny, Mario Maas, Aeilko H. Zwinderman, Colin J.D. Ross, Eleonora Aronica, Katherine A. High, Marcel M. Levi, Michael R. Hayden, John J.P. Kastelein, Jan Albert Kuivenhoven
2008146
6
Effect of Alipogene Tiparvovec (AAV1-LPLS447X) on Postprandial Chylomicron Metabolism in Lipoprotein Lipase-Deficient Patients
The Journal of Clinical Endocrinology & Metabolism ·André C. Carpentier, Frédérique Frisch, Sébastien M. Labbé, René Gagnon, J. de Wal, S. Greentree, Harald Petry, Jaap Twisk, Diane Brisson, Daniel Gaudet
2012123
7
Phase I open label liver-directed gene therapy clinical trial for acute intermittent porphyria
Journal of Hepatology ·Delia D’Avola, Esperanza López‐Franco, Bruno Sangro, Astrid Pañeda, Nadina Grossios, Irene Gil-Fariña, Alberto Benito, Jaap Twisk, María de la Paz, Juan Ruiz, Manfred Schmidt, Harald Petry, Pauline Harper, Rafael Enrı́quez de Salamanca, Antonio Fontanellas, Jesús Prìeto, Gloria González‐Aseguinolaza
2016113
8
Scavenger receptor class B type I is solely responsible for the selective uptake of cholesteryl esters from HDL by the liver and the adrenals in mice
Journal of Lipid Research ·Ruud Out, Menno Hoekstra, John A.A. Spijkers, J. Kar Kruijt, Miranda Van Eck, Ingrid S.T. Bos, Jaap Twisk, Theo J.C. van Berkel
2004110
9
Cellular tropism and transduction properties of seven adeno-associated viral vector serotypes in adult retina after intravitreal injection
Gene Therapy ·Mats Hellström, Marc J. Ruitenberg, Marcaket Pollett, Erich Ehlert, Jaap Twisk, Joost Verhaagen, Alan R. Harvey
2008110
10
Immune Responses to Intramuscular Administration of Alipogene Tiparvovec (AAV1-LPL S447X ) in a Phase II Clinical Trial of Lipoprotein Lipase Deficiency Gene Therapy
Human Gene Therapy ·Valérie Ferreira, Jaap Twisk, Karin L. Kwikkers, Eleonora Aronica, Diane Brisson, Julie Méthot, Harald Petry, Daniel Gaudet
2013107
11
Insulin suppresses bile acid synthesis in cultured rat hepatocytes by down-regulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase gene transcription
Hepatology ·Jaap Twisk, Marco F.M. Hoekman, Eline M. Lehmann, Piet Meijer, Willem H. Mager, (unknown)
199597
12
Aorta of ApoE-Deficient Mice Responds to Atherogenic Stimuli by a Prelesional Increase and Subsequent Decrease in the Expression of Antioxidant Enzymes
Circulation Research ·Peter A.C. ’t Hoen, Christian A.C. van der Lans, Miranda Van Eck, Martin K. Bijsterbosch, Theo J.C. van Berkel, Jaap Twisk
200397
13
Effect of Adeno-Associated Virus Serotype and Genomic Structure on Liver Transduction and Biodistribution in Mice of Both Genders
Human Gene Therapy ·Astrid Pañeda, Lucía Vanrell, Itsaso Mauleón, Julien Crettaz, Pedro Berraondo, Eric Timmermans, Stuart G. Beattie, Jaap Twisk, Sander van Deventer, Jesús Prìeto, Antonio Fontanellas, Maria Sol Rodríguez-Peña, Gloria González‐Aseguinolaza
200988
14
Regulation of Bile Acid Biosynthesis
Current Pharmaceutical Design ·(unknown), Sabine M. Post, Jaap Twisk
199787
15
Adeno-associated Virus Vector Serotypes Mediate Sustained Correction of Bilirubin UDP Glucuronosyltransferase Deficiency in Rats
Molecular Therapy ·Jurgen Seppen, Conny Bakker, Berry de Jong, Cindy Kunne, Karin van den Oever, Kristin Vandenberghe, Rudi de Waart, Jaap Twisk, Piter J. Bosma
200669
16
Heterogeneous expression of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase genes in the rat liver lobulus.
Journal of Clinical Investigation ·Jaap Twisk, Marco F.M. Hoekman, W.H. Mager, Antoon F.M. Moorman, Piet A. J. de Boer, Ludger Scheja, (unknown), Rolf Gebhardt
199563
17
Long-Term Correction of Murine Lipoprotein Lipase Deficiency with AAV1-Mediated Gene Transfer of the Naturally Occurring LPL S447X Beneficial Mutation
Human Gene Therapy ·Colin J.D. Ross, Jaap Twisk, Janneke M. Meulenberg, Guoqing Liu, Karin van den Oever, Ewoud Moraal, Wim Th. Hermens, Jaap Rip, John J.P. Kastelein, Jan Albert Kuivenhoven, Michael R. Hayden
200463
18
Differential feedback regulation of cholesterol 7α-hydroxylase mRNA and transcriptional activity by rat bile acids in primary monolayer cultures of rat hepatocytes
Biochemical Journal ·Jaap Twisk, Eline M. Lehmann, (unknown)
199362
19
Correction of Feline Lipoprotein Lipase Deficiency with Adeno-Associated Virus Serotype 1-Mediated Gene Transfer of the Lipoprotein Lipase S447X Beneficial Mutation
Human Gene Therapy ·Colin J.D. Ross, Jaap Twisk, Andrew C. Bakker, Fudan Miao, Dennis Verbart, Jaap Rip, Tamara Godbey, Paul A. Dijkhuizen, Wim Th. Hermens, John J.P. Kastelein, Jan Albert Kuivenhoven, Janneke M. Meulenberg, Michael R. Hayden
200660
20
Complete Rescue of Lipoprotein Lipase–Deficient Mice by Somatic Gene Transfer of the Naturally Occurring LPLS447XBeneficial Mutation
Arteriosclerosis Thrombosis and Vascular Biology ·Colin J.D. Ross, Guoqing Liu, Jan Albert Kuivenhoven, Jaap Twisk, Jaap Rip, Willemijn van Dop, Katherine J. D. A. Excoffon, M. E. Suzanne Lewis, John J.P. Kastelein, Michael R. Hayden
200555

About Jaap Twisk

Jaap Twisk is a scholar working on Genetics, Surgery, Oncology, Molecular Biology and Cardiology and Cardiovascular Medicine, having authored 49 papers that have together received 2.9k indexed citations. Recurring topics across this work include Cholesterol and Lipid Metabolism (15 papers), Drug Transport and Resistance Mechanisms (12 papers), Virus-based gene therapy research (12 papers), Diabetes and associated disorders (11 papers), Lipid metabolism and disorders (8 papers), Liver Disease Diagnosis and Treatment (4 papers), Cancer, Lipids, and Metabolism (4 papers) and Peroxisome Proliferator-Activated Receptors (4 papers). The work is most often cited by research in Genetics (824 citations), Endocrinology, Diabetes and Metabolism (416 citations), Oncology (651 citations), Surgery (1.0k citations) and Cardiology and Cardiovascular Medicine (487 citations). Jaap Twisk has collaborated with scholars based in Netherlands, Canada and United States. Frequent co-authors include Theo J.C. van Berkel, Miranda Van Eck, Diane Brisson, Daniel Gaudet, I. Sophie T. Bos, Julie Méthot, Jan Albert Kuivenhoven, J. de Wal, John J.P. Kastelein and Menno Hoekstra. Their work appears in journals such as Human Gene Therapy, Biochemical Journal, Arteriosclerosis Thrombosis and Vascular Biology, Gene and Journal of Lipid Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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