J. Breed

4.8k citations

54 papers · 3.6k · h-index 34

Impact in

Molecular Biology top 5%
- Lipid Membrane Structure and Behavior
- Protein Structure and Dynamics
- Ion channel regulation and function
- RNA and protein synthesis mechanisms
- Fibroblast Growth Factor Research
Oncology top 5%

Papers in

Molecular Biology 43
- Lipid Membrane Structure and Behavior 7
- Chemical Synthesis and Analysis 6
- Biochemical and Molecular Research 4
- Protein Structure and Dynamics 4
Cell Biology 9
- Microtubule and mitosis dynamics 4

Co-authors: Mark S.P. Sansom (15 shared papers)Ian D. Kerr (8 shared papers)Richard A. Norman (8 shared papers)Ramasubbu Sankararamakrishnan (6 shared papers)Wolfram Welte (9 shared papers)Oliver S. Smart (2 shared papers)Kay Diederichs (7 shared papers)Graham R. Smith (1 shared paper)
Journals: Bioorganic & Medicinal Chemistry Letters (7 papers)Biophysical Journal (6 papers)Biochemistry (4 papers)Journal of Medicinal Chemistry (4 papers)Structure (3 papers)
Partner nations: United Kingdom Germany United States

In The Last Decade

J. Breed

53 papers receiving 3.5k citations

Peers

Countries citing papers authored by J. Breed

Since Specialization

Citations

This map shows the geographic impact of J. Breed's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by J. Breed with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites J. Breed more than expected).

Fields of papers citing papers by J. Breed

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by J. Breed. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by J. Breed. The network helps show where J. Breed may publish in the future.

Co-authors

The 25 scholars most cited alongside J. Breed, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with J. Breed Line = papers co-authored together J. Breed links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Showing the 20 most-cited of 54 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Phase Ib Trial of Intravenous Recombinant Humanized Monoclonal Antibody to Vascular Endothelial Growth Factor in Combination With Chemotherapy in Patients With Advanced Cancer: Pharmacologic and Long-Term Safety Data Journal of Clinical Oncology ·Kim Margolin, Michael Gordon, Eric Holmgren, Jacques Gaudreault, William Novotny, G. Fyfe, Daniel C. Adelman, Susan Stalter, J. Breed	2001	315
2	N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a Novel, Highly Selective, Orally Available, Dual-Specific c-Src/Abl Kinase Inhibitor Journal of Medicinal Chemistry ·Laurent Hennequin, J M Allen, J. Breed, Jon Curwen, Michael Fennell, Tim P. Green, Christine Lambert‐van der Brempt, Rémy Morgentin, Richard A. Norman, Annie Olivier, Ludovic R. Otterbein, Patrick A. Plé, Nicolas Warin, Gerard Costello	2006	302
3	A novel method for structure-based prediction of ion channel conductance properties Biophysical Journal ·Oliver S. Smart, J. Breed, Graham R. Smith, Mark S.P. Sansom	1997	190
4	Structure and Interactions of NCAM Ig1-2-3 Suggest a Novel Zipper Mechanism for Homophilic Adhesion Structure ·Vladislav Soroka, Kateryna Kolkova, J.S. Kastrup, Kay Diederichs, J. Breed, Vladislav V. Kiselyov, Flemming M. Poulsen, Ingrid Kjøller Larsen, Wolfram Welte, Vladimir Berezin, Elisabeth Bock, Christina Kasper	2003	152
5	Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13Rα1 and IL-13Rα2 Journal of Molecular Biology ·Bojana Popovic, J. Breed, D. Gareth Rees, Matthew Gardener, Lisa Vinall, Benjamin Kemp, Jennifer Spooner, Jennifer Keen, Ralph Minter, Ferzan Uddin, Gene Colice, T. Wilkinson, Tristan J. Vaughan, Richard May	2016	151
6	A study of the reactivity of S^(VI)–F containing warheads with nucleophilic amino-acid side chains under physiological conditions Organic & Biomolecular Chemistry ·H. G. MUKHERJEE, J.E. Debreczeni, J. Breed, Sharon Tentarelli, Brian Aquila, James J. Dowling, Adrian Whitty, Neil P. Grimster	2017	136
7	Water in channel-like cavities: structure and dynamics Biophysical Journal ·Mark S.P. Sansom, Ian D. Kerr, J. Breed, Ramasubbu Sankararamakrishnan	1996	124
8	Cation-π Interactions as Determinants for Binding of the Compatible Solutes Glycine Betaine and Proline Betaine by the Periplasmic Ligand-binding Protein ProX from Escherichia coli Journal of Biological Chemistry ·A. Schiefner, J. Breed, Linda Bösser, Susanne Kneip, Jutta Gade, (unknown), Kay Diederichs, Wolfram Welte, Erhard Bremer	2004	108
9	SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·Nicola M. Heron, Malcolm Anderson, David P. Blowers, J. Breed, Jonathan Eden, Stephen Green, George B. Hill, Trevor Johnson, Frédéric Jung, Helen McMiken, Andrew Mortlock, Andrew Pannifer, Richard A. Pauptit, Jennifer H. Pink, Nicola Roberts, Siân Rowsell	2005	106
10	Imidazo[1,2-a]pyridines: A potent and selective class of cyclin-Dependent kinase inhibitors identified through structure-Based hybridisation Bioorganic & Medicinal Chemistry Letters ·Malcolm Anderson, John F. Beattie, Gloria A. Breault, J. Breed, Kate Byth, Janet D. Culshaw, Rebecca Ellston, Stephen Green, Claire A. Minshull, Richard A. Norman, Richard A. Pauptit, J. Stanway, Andrew P. Thomas, Philip J. Jewsbury	2003	103
11	Potent and Selective Inhibitors of MTH1 Probe Its Role in Cancer Cell Survival Journal of Medicinal Chemistry ·Jason G. Kettle, Husam Alwan, Michał Biśta, J. Breed, Nichola L. Davies, Kay Eckersley, Shaun Fillery, Kevin M. Foote, Louise Goodwin, David R. Jones, Helena Käck, Alan Lau, J. Willem M. Nissink, Jon Read, James S. Scott, Ben Taylor, Graeme E. Walker, Lisa Wissler, Marta Wylot	2016	103
12	Structural Insights into FGFR Kinase Isoform Selectivity: Diverse Binding Modes of AZD4547 and Ponatinib in Complex with FGFR1 and FGFR4 Structure ·Julie A. Tucker, Tobias Klein, J. Breed, Alexander L. Breeze, R. Overman, Chris Phillips, Richard A. Norman	2014	101
13	Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical use Oncotarget ·Harshnira Hitesh Patani, Tom D. Bunney, Nethaji Thiyagarajan, Richard A. Norman, D. Ogg, J. Breed, Paul Ashford, Andrew Potterton, Mina Edwards, Sarah V. Williams, Gary S. Thomson, Camilla Pang, Margaret A. Knowles, Alexander L. Breeze, Christine Orengo, Chris Phillips, Matilda Katan	2016	94
14	Crystal Structure of Human Thymidine Phosphorylase in Complex with a Small Molecule Inhibitor Structure ·Richard A. Norman, Simon T. Barry, Michael Bate, J. Breed, Jeremy G. Colls, Richard J. Ernill, Richard Luke, Claire A. Minshull, M. McAlister, Eileen McCall, Helen McMiken, D. Paterson, David Timms, Julie A. Tucker, Richard A. Pauptit	2004	90
15	Conservation analysis and structure prediction of the SH2 family of phosphotyrosine binding domains FEBS Letters ·Robert B. Russell, J. Breed, Geoffrey J. Barton	1992	86
16	Molecular dynamics simulations of water within models of ion channels Biophysical Journal ·J. Breed, Ramasubbu Sankararamakrishnan, Ian D. Kerr, Mark S.P. Sansom	1996	85
17	Prediction by a neural network of outer membrane β‐strand protein topology Protein Science ·Kay Diederichs, Jörg Freigang, Stephan Umhau, Kornelius Zeth, J. Breed	1998	79
18	Prevention of MKK6-Dependent Activation by Binding to p38α MAP Kinase Biochemistry ·Jane E. Sullivan, Geoffrey A. Holdgate, Douglas A. Campbell, David Timms, S. Gerhardt, J. Breed, Alexander L. Breeze, Alun Bermingham, Richard A. Pauptit, Richard A. Norman, Kevin J. Embrey, Jon Read, Wendy S. VanScyoc, Walter H.J. Ward	2005	76
19	Structural and functional characterization of a DARPin which inhibits Ras nucleotide exchange Nature Communications ·Sandrine Guillard, Paulina Kolasinska-Zwierz, J.E. Debreczeni, J. Breed, Jing Zhang, Nicolas Béry, Rose Marwood, Jon Tart, R. Overman, Paweł Stocki, (unknown), Christopher Phillips, Terence H. Rabbitts, Ronald H. Jackson, Ralph Minter	2017	75
20	Molecular Determinants for Substrate Specificity of the Ligand-binding Protein OpuAC from Bacillus subtilis for the Compatible Solutes Glycine Betaine and Proline Betaine Journal of Molecular Biology ·Carsten Horn, Linda Sohn-Bösser, J. Breed, Wolfram Welte, Lutz Schmitt, Erhard Bremer	2006	74

About J. Breed

J. Breed is a scholar working on Molecular Biology, Cell Biology, Organic Chemistry, Atomic and Molecular Physics, and Optics and Oncology, having authored 54 papers that have together received 3.6k indexed citations. Recurring topics across this work include Lipid Membrane Structure and Behavior (7 papers), Enzyme Structure and Function (6 papers), Chemical Synthesis and Analysis (6 papers), Mass Spectrometry Techniques and Applications (5 papers), Microtubule and mitosis dynamics (4 papers), Biochemical and Molecular Research (4 papers), Nanopore and Nanochannel Transport Studies (4 papers) and Protein Structure and Dynamics (4 papers). The work is most often cited by research in Molecular Biology (2.4k citations), Oncology (574 citations), Immunology and Allergy (118 citations), Microbiology (109 citations) and Organic Chemistry (529 citations). J. Breed has collaborated with scholars based in United Kingdom, Germany and United States. Frequent co-authors include Mark S.P. Sansom, Ian D. Kerr, Richard A. Norman, Ramasubbu Sankararamakrishnan, Wolfram Welte, Oliver S. Smart, Kay Diederichs, Graham R. Smith, Kim Margolin and Michael Gordon. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Biophysical Journal, Biochemistry, Journal of Medicinal Chemistry and Structure.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

J. Breed

Impact in

Papers in i

In The Last Decade

J. Breed

Peers

Countries citing papers authored by J. Breed

Fields of papers citing papers by J. Breed

All Works

About J. Breed

Explore authors with similar magnitude of impact

Papers in