Douglas Hedley

2.1k citations

45 papers · 1.4k · h-index 15

Impact in

Oncology top 5%
- Cutaneous Melanoma Detection and Management
Biotechnology top 5%
- Cancer Research and Treatments

Papers in

Philosophy 14
- Classical Philosophy and Thought 6
- Religious Studies and Spiritual Practices 3
Molecular Biology 12
- Melanoma and MAPK Pathways 9

Co-authors: Lesley Ogilvie (15 shared papers)Caroline J. Springer (15 shared papers)Richard Marais (13 shared papers)Jan Martin (5 shared papers)Dan Niculescu‐Duvaz (7 shared papers)Maria Karasarides (2 shared papers)Robert Hayward (3 shared papers)Frank Friedlos (9 shared papers)
Journals: Journal of Medicinal Chemistry (5 papers)Cancer Research (5 papers)Journal of the History of Ideas (2 papers)International Journal for the Study of the Christian Church (1 paper)Clinical Cancer Research (1 paper)
Partner nations: United Kingdom United States South Sudan

In The Last Decade

Douglas Hedley

33 papers receiving 1.3k citations

Peers

Countries citing papers authored by Douglas Hedley

Since Specialization

Citations

This map shows the geographic impact of Douglas Hedley's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Douglas Hedley with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Douglas Hedley more than expected).

Fields of papers citing papers by Douglas Hedley

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Douglas Hedley. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Douglas Hedley. The network helps show where Douglas Hedley may publish in the future.

Co-authors

The 25 scholars most cited alongside Douglas Hedley, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Douglas Hedley Line = papers co-authored together Douglas Hedley links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 45 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	B-RAF is a therapeutic target in melanoma Oncogene ·Maria Karasarides, Antonio Chiloeches, Robert Hayward, Dan Niculescu‐Duvaz, Ian Scanlon, Frank Friedlos, Lesley Ogilvie, Douglas Hedley, Jan Martin, Christopher J. Marshall, Caroline J. Springer, Richard Marais	2004	360
2	V599EB-RAF is an Oncogene in Melanocytes Cancer Research ·Claudia Wellbrock, Lesley Ogilvie, Douglas Hedley, Maria Karasarides, Jan Martin, Dan Niculescu‐Duvaz, Caroline J. Springer, Richard Marais	2004	272
3	In Melanoma, RAS Mutations Are Accompanied by Switching Signaling from BRAF to CRAF and Disrupted Cyclic AMP Signaling Cancer Research ·Nicolas Dumaz, Robert Hayward, Jan Martin, Lesley Ogilvie, Douglas Hedley, John A. Curtin, Boris C. Bastian, Caroline J. Springer, Richard Marais	2006	241
4	Attenuated Salmonella Targets Prodrug Activating Enzyme Carboxypeptidase G2 to Mouse Melanoma and Human Breast and Colon Carcinomas for Effective Suicide Gene Therapy Clinical Cancer Research ·Frank Friedlos, Panos Lehouritis, Lesley Ogilvie, Douglas Hedley, Lawrence Davies, David Bermudes, Ivan King, Jan Martin, Richard Marais, Caroline J. Springer	2008	76
5	Carboxypeptidase G2-based gene-directed enzyme–prodrug therapy: a new weapon in the GDEPT armoury Nature reviews. Cancer ·Douglas Hedley, Lesley Ogilvie, Caroline J. Springer	2007	59
6	Suicide Gene Therapy of Human Colon Carcinoma Xenografts Using an Armed Oncolytic Adenovirus Expressing Carboxypeptidase G2 Cancer Research ·Silke Schepelmann, Lesley Ogilvie, Douglas Hedley, Frank Friedlos, Janet L. Martin, Ian Scanlon, Ping Chen, Richard Marais, Caroline J. Springer	2007	50
7	Pyridoimidazolones as Novel Potent Inhibitors of v-Raf Murine Sarcoma Viral Oncogene Homologue B1 (BRAF) Journal of Medicinal Chemistry ·Dan Niculescu‐Duvaz, Catherine Gaulon, H.P. Dijkstra, Ion Niculescu‐Duvaz, Alfonso Zambon, Delphine Ménard, Bart M. J. M. Suijkerbuijk, Arnaud Nourry, Lawrence Davies, Helen Manne, Frank Friedlos, Lesley Ogilvie, Douglas Hedley, Steven R. Whittaker, (unknown), Adrian L. Gill, Richard D. Taylor, Florence I. Raynaud, Javier Moreno‐Farre, Richard Marais, Caroline J. Springer	2009	33
8	Novel Hinge Binder Improves Activity and Pharmacokinetic Properties of BRAF Inhibitors Journal of Medicinal Chemistry ·Alfonso Zambon, Delphine Ménard, Bart M. J. M. Suijkerbuijk, Ion Niculescu‐Duvaz, Steven R. Whittaker, Dan Niculescu‐Duvaz, Arnaud Nourry, Lawrence Davies, Helen Manne, Filipa M. Lopes, Natasha Preece, Douglas Hedley, Lesley Ogilvie, (unknown), Richard Marais, Caroline J. Springer	2010	31
9	Novel tricyclic pyrazole BRAF inhibitors with imidazole or furan central scaffolds Bioorganic & Medicinal Chemistry ·Dan Niculescu‐Duvaz, Ion Niculescu‐Duvaz, Bart M. J. M. Suijkerbuijk, Delphine Ménard, Alfonso Zambon, Arnaud Nourry, Lawrence Davies, Helen Manne, Frank Friedlos, Lesley Ogilvie, Douglas Hedley, Andrew K. Takle, David M. Wilson, Jean‐François Pons, Tom Coulter, (unknown), Neus Cantariño, Steven R. Whittaker, Richard Marais, Caroline J. Springer	2010	28
10	Systemic Gene-Directed Enzyme Prodrug Therapy of Hepatocellular Carcinoma Using a Targeted Adenovirus Armed with Carboxypeptidase G2 Cancer Research ·Silke Schepelmann, Paul L. Hallenbeck, Lesley Ogilvie, Douglas Hedley, Frank Friedlos, Janet L. Martin, Ian Scanlon, Carl Hay, Lynda K. Hawkins, Richard Marais, Caroline J. Springer	2005	27
11	Novel Fluorinated Prodrugs for Activation by Carboxypeptidase G2 Showing Good in Vivo Antitumor Activity in Gene-Directed Enzyme Prodrug Therapy Journal of Medicinal Chemistry ·Lawrence Davies, Frank Friedlos, Douglas Hedley, Jan Martin, Lesley Ogilvie, Ian Scanlon, Caroline J. Springer	2005	24
12	Development of Novel, Highly Potent Inhibitors of V-RAF Murine Sarcoma Viral Oncogene Homologue B1 (BRAF): Increasing Cellular Potency through Optimization of a Distal Heteroaromatic Group Journal of Medicinal Chemistry ·Bart M. J. M. Suijkerbuijk, Ion Niculescu‐Duvaz, Catherine Gaulon, H.P. Dijkstra, Dan Niculescu‐Duvaz, Delphine Ménard, Alfonso Zambon, Arnaud Nourry, Lawrence Davies, Helen Manne, Frank Friedlos, Lesley Ogilvie, Douglas Hedley, Filipa M. Lopes, Natasha Preece, Javier Moreno‐Farre, Florence I. Raynaud, (unknown), Steven R. Whittaker, Richard Marais, Caroline J. Springer	2010	24
13	Inducible expression of^V600EBraf using tyrosinase-driven Cre recombinase results in embryonic lethality Pigment Cell & Melanoma Research ·Nathalie Dhomen, Silvy da Rocha Dias, Robert Hayward, Lesley Ogilvie, Douglas Hedley, Véronique Delmas, Afshan McCarthy, Deborah J. Henderson, Caroline J. Springer, Catrin Pritchard, Lionel Larue, Richard Marais	2009	19
14	Coleridge, Philosophy and Religion Cambridge University Press eBooks ·Douglas Hedley	2000	16
15	A Novel, Selective, and Efficacious Nanomolar Pyridopyrazinone Inhibitor of V600EBRAF Cancer Research ·Steven R. Whittaker, Delphine Ménard, (unknown), Lesley Ogilvie, Douglas Hedley, Alfonso Zambon, Filipa M. Lopes, Natasha Preece, Helen Manne, Sareena Rana, Maryou Lambros, Jorge S. Reis‐Filho, Richard Marais, Caroline J. Springer	2010	15
16	Proinsecticides effective against insecticide‐resistant peach‐potato aphid ( Myzus persicae (Sulzer)) Pesticide Science ·Douglas Hedley, Bhupinder P. S. Khambay, Antony M. Hooper, Richard Thomas, A. L. Devonshire	1998	13
17	Coleridge, Philosophy and Religion: Aids to Reflection and the Mirror of the Spirit Medical Entomology and Zoology ·Douglas Hedley	2000	13
18	Platonism at the origins of modernity : studies on Platonism and early modern philosophy Digital Access to Libraries (Université catholique de Louvain (UCL), l'Université de Namur (UNamur) and the Université Saint-Louis (USL-B)) ·Douglas Hedley, Sarah Hutton	2008	12
19	Living forms of the imagination Douglas Hedley	2008	10
20	WHAT IS THE POINT OF BEING A CHRISTIAN TLS, the Times literary supplement/Times literary supplement on CD-ROM/TLS. Times literary supplement ·Douglas Hedley	2006	6

About Douglas Hedley

Douglas Hedley is a scholar working on Philosophy, Molecular Biology, Oncology, History and Sociology and Political Science, having authored 45 papers that have together received 1.4k indexed citations. Recurring topics across this work include Melanoma and MAPK Pathways (9 papers), Classical Philosophy and Thought (6 papers), Cancer Research and Treatments (5 papers), Cancer Mechanisms and Therapy (4 papers), Cytokine Signaling Pathways and Interactions (4 papers), Virus-based gene therapy research (4 papers), Religious Studies and Spiritual Practices (3 papers) and Biblical Studies and Interpretation (2 papers). The work is most often cited by research in Oncology (431 citations), Biotechnology (130 citations), Molecular Biology (964 citations), Computational Theory and Mathematics (172 citations) and Cell Biology (150 citations). Douglas Hedley has collaborated with scholars based in United Kingdom, United States and South Sudan. Frequent co-authors include Lesley Ogilvie, Caroline J. Springer, Richard Marais, Jan Martin, Dan Niculescu‐Duvaz, Maria Karasarides, Robert Hayward, Frank Friedlos, Ian Scanlon and Claudia Wellbrock. Their work appears in journals such as Journal of Medicinal Chemistry, Cancer Research, Journal of the History of Ideas, International Journal for the Study of the Christian Church and Clinical Cancer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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