Cor Breukel

4.4k citations

55 papers · 3.5k · 1 hit paper · h-index 27

Impact in

Pathology and Forensic Medicine top 0.5%
- Genetic factors in colorectal cancer
Oncology top 2%
- Colorectal Cancer Treatments and Studies
- Cancer Cells and Metastasis
- Cancer-related Molecular Pathways

Papers in

Molecular Biology 27
- Wnt/β-catenin signaling in development and cancer 9
- Cancer-related gene regulation 6
- RNA Research and Splicing 5
Pathology and Forensic Medicine 25
- Genetic factors in colorectal cancer 24

Co-authors: Riccardo Fodde (25 shared papers)Ron Smits (12 shared papers)P. Meera Khan (20 shared papers)Cláudia Gaspar (4 shared papers)Menno F. Kielman (5 shared papers)Winfried Edelmann (4 shared papers)Carli M.J. Tops (15 shared papers)C. van Leeuwen (6 shared papers)
Journals: Nucleic Acids Research (9 papers)Human Genetics (4 papers)The Journal of Immunology (4 papers)Genes Chromosomes and Cancer (3 papers)Gastroenterology (3 papers)
Partner nations: Netherlands United States United Kingdom

In The Last Decade

Cor Breukel

54 papers receiving 3.3k citations

Cor Breukel's Hit Papers

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Mutations in the APC tumour suppressor gene cause chromosomal instability 2001 · 594 citations

Peers

Countries citing papers authored by Cor Breukel

Since Specialization

Citations

This map shows the geographic impact of Cor Breukel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Cor Breukel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Cor Breukel more than expected).

Fields of papers citing papers by Cor Breukel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Cor Breukel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Cor Breukel. The network helps show where Cor Breukel may publish in the future.

Co-authors

The 25 scholars most cited alongside Cor Breukel, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Cor Breukel Line = papers co-authored together Cor Breukel links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

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#	Work
1	Mutations in the APC tumour suppressor gene cause chromosomal instability Nature Cell Biology ·Riccardo Fodde, Jeroen Kuipers, Carla Rosenberg, Ron Smits, Menno F. Kielman, Cláudia Gaspar, Johan H. van Es, Cor Breukel, J. Wiegant, Rachel H. Giles, Hans Clevers Hit paper breakdown →	2001	594
2	A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors. Proceedings of the National Academy of Sciences ·Riccardo Fodde, Winfried Edelmann, Kan Yang, C. van Leeuwen, Christine Carlson, Beatrice Renault, Cor Breukel, Eckhard Alt, Mack Lipkin, P. Meera Khan	1994	458
3	Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catenin signaling Nature Genetics ·Menno F. Kielman, Maaret Rindapää, Cláudia Gaspar, Nicole van Poppel, Cor Breukel, Sandra van Leeuwen, Makoto M. Taketo, Scott J. Roberts, Ron Smits, Riccardo Fodde	2002	305
4	APC and Oncogenic KRAS Are Synergistic in Enhancing Wnt Signaling in Intestinal Tumor Formation and Progression Gastroenterology ·Klaus‐Peter Janssen, Paola Alberici, Hafida Fsihi, Cláudia Gaspar, Cor Breukel, Patrick Franken, Christophe Rosty, Miguel Abal, Fatima El Marjou, Ron Smits, Daniel Louvard, Riccardo Fodde, Sylvie Robine	2006	246
5	Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development Genes & Development ·Ron Smits, Menno F. Kielman, Cor Breukel, C. Zurcher, Kristi L. Neufeld, S. Jagmohan-Changur, Nandy Hofland, Joanke Van Dijk, R. White, Winfried Edelmann, Raju Kucherlapati, P. Meera Khan, Riccardo Fodde	1999	204
6	Hereditary desmoid disease due to a frameshift mutation at codon 1924 of the APC gene. PubMed Central ·Diana Eccles, Rob B. van der Luijt, Cor Breukel, H. Bullman, David J. Bunyan, Azetta Fisher, John Barber, Clotilde Boulay, John Primrose, John Burn, Riccardo Fodde	1996	158
7	Germline mutations in the 3′ part of APC exon 15 do not result in truncated proteins and are associated with attenuated adenomatous polyposis coli Human Genetics ·Rob B. van der Luijt, P. Meera Khan, Hans F. A. Vasen, Cor Breukel, Carli M.J. Tops, Rodney J. Scott, Riccardo Fodde	1996	128
8	Apc1638N: A mouse model for familial adenomatous polyposis–associated desmoid tumors and cutaneous cysts Gastroenterology ·Ron Smits, Willemien van der Houven van Oordt, Arne Luz, C. Zurcher, Shantie Jagmohan–Changur, Cor Breukel, P. Meera Khan, Riccardo Fodde	1998	120
9	APC mutation in the alternatively spliced region of exon 9 associated with late onset familial adenomatous polyposis Human Genetics ·Rob B. van der Luijt, Hans F. A. Vasen, Carli M.J. Tops, Cor Breukel, Riccardo Fodde, P. Meera Khan	1995	100
10	The Inhibiting Fc Receptor for IgG, FcγRIIB, Is a Modifier of Autoimmune Susceptibility The Journal of Immunology ·Péter Boross, Victoria L. Arandhara, Javier Martín-Ramírez, Marie-Laure Santiago-Raber, Francesco Carlucci, Roelof Flierman, Jos van der Kaa, Cor Breukel, Jill Claassens, Marcel Camps, Erik Lubberts, Daniela Salvatori, Maria Pia Rastaldi, Ferry Ossendorp, Mohamed R. Daha, H. Terence Cook, Shozo Izui, Marina Botto, J. Sjef Verbeek	2011	94
11	SomaticApc mutations are selected upon their capacity to inactivate the ?-catenin downregulating activity Genes Chromosomes and Cancer ·Ron Smits, Nandy Hofland, Winfried Edelmann, Marjan Geugien, Shantie Jagmohan–Changur, Cristina Albuquerque, Cor Breukel, Raju Kucherlapati, Menno F. Kielman, Riccardo Fodde	2000	79
12	Close linkage of a highly polymorphic marker (D5S37) to familial adenomatous polyposis (FAP) and confirmation of FAP localization on chromosome 5q21-q22 Human Genetics ·P. Meera Khan, Carli M.J. Tops, Marcel van den Broek, Cor Breukel, Juul Wijnen, M. Oldenburg, Jetske van der Bos, Inge S. J. Van Leeuwen‐Cornelisse, Hans F. A. Vasen, G Griffioen, H. M. Verspaget, F.C.A. den Hartog Jager	1988	72
13	A Targeted Constitutive Mutation in the Apc Tumor Suppressor Gene Underlies Mammary But Not Intestinal Tumorigenesis PLoS Genetics ·Cláudia Gaspar, Patrick Franken, Lia Molenaar, Cor Breukel, Martin van der Valk, Ron Smits, Riccardo Fodde	2009	64
14	A new conditional Apc-mutant mouse model for colorectal cancer Carcinogenesis ·Els C. Robanus-Maandag, Pim J. Koelink, Cor Breukel, Daniela Salvatori, S. Jagmohan-Changur, Cathy A.J. Bosch, Hein W. Verspaget, Peter Devilee, Riccardo Fodde, Ron Smits	2010	64
15	First FHM3 mouse model shows spontaneous cortical spreading depolarizations Annals of Clinical and Translational Neurology ·Nico A. Jansen, Anisa Dehghani, Margot M. Linssen, Cor Breukel, Else A. Tolner, Arn M. J. M. van den Maagdenberg	2019	56
16	A targeted mouse Brca1 mutation removing the last BRCT repeat results in apoptosis and embryonic lethality at the headfold stage Oncogene ·Peter Hohenstein, Menno F. Kielman, Cor Breukel, L. Michelle Bennett, Roger W. Wiseman, Paul Krimpenfort, Cees J. Cornelisse, Gert‐Jan B. van Ommen, Peter Devilee, Riccardo Fodde	2001	51
17	A dystrophic Duchenne mouse model for testing human antisense oligonucleotides PLoS ONE ·Marcel H. A. M. Veltrop, Laura Van de Vliet, Margriet Hulsker, Jill Claassens, Conny Brouwers, Cor Breukel, Jos van der Kaa, Margot M. Linssen, Johan T. den Dunnen, Sjef Verbeek, Annemieke Aartsma‐Rus, Maaike van Putten	2018	50
18	A 10‐Mb paracentric inversion of chromosome arm 2p inactivates MSH2 and is responsible for hereditary nonpolyposis colorectal cancer in a North‐American kindred Genes Chromosomes and Cancer ·Anja Wagner, Heleen van der Klift, Patrick Franken, Juul Wijnen, Cor Breukel, Vladimir Bezrookove, Ron Smits, Yulia Kinarsky, Alicia Barrows, Barbara Franklin, Jane F. Lynch, Henry T. Lynch, Riccardo Fodde	2002	49
19	E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice Gastroenterology ·Ron Smits, Patricia Ruíz, Salvador J. Díaz‐Cano, Arne Luz, Shantie Jagmohan–Changur, Cor Breukel, Carmen Birchmeier, Walter Birchmeier, Riccardo Fodde	2000	48
20	Vector-Alu PCR: a rapid step in mapping cosmids and YACs Nucleic Acids Research ·Cor Breukel, JT Wijnen, C.M.J. Tops, H.v d Klift, Hans G. Dauwerse, P. Meera Khan	1990	48

About Cor Breukel

Cor Breukel is a scholar working on Molecular Biology, Pathology and Forensic Medicine, Oncology, Cancer Research and Genetics, having authored 55 papers that have together received 3.5k indexed citations. Recurring topics across this work include Genetic factors in colorectal cancer (24 papers), Cancer Genomics and Diagnostics (10 papers), Wnt/β-catenin signaling in development and cancer (9 papers), Monoclonal and Polyclonal Antibodies Research (6 papers), Cancer-related gene regulation (6 papers), Colorectal Cancer Treatments and Studies (5 papers), RNA Research and Splicing (5 papers) and Adenosine and Purinergic Signaling (4 papers). The work is most often cited by research in Pathology and Forensic Medicine (1.4k citations), Oncology (1.0k citations), Cancer Research (500 citations), Molecular Biology (1.9k citations) and Genetics (493 citations). Cor Breukel has collaborated with scholars based in Netherlands, United States and United Kingdom. Frequent co-authors include Riccardo Fodde, Ron Smits, P. Meera Khan, Cláudia Gaspar, Menno F. Kielman, Winfried Edelmann, Carli M.J. Tops, C. van Leeuwen, Rachel H. Giles and Hans Clevers. Their work appears in journals such as Nucleic Acids Research, Human Genetics, The Journal of Immunology, Genes Chromosomes and Cancer and Gastroenterology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Cor Breukel

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