Cor Breukel

4.5k citations

58 papers · 3.6k · 1 hit paper · h-index 28

Impact in

Pathology and Forensic Medicine top 0.5%
- Genetic factors in colorectal cancer
Oncology top 5%
- Cancer Cells and Metastasis
- Colorectal Cancer Treatments and Studies
- Cancer-related Molecular Pathways

Papers in

Pathology and Forensic Medicine 29
- Genetic factors in colorectal cancer 29
Molecular Biology 17
- Wnt/β-catenin signaling in development and cancer 5
- Biochemical and Molecular Research 4

Co-authors: Riccardo Fodde (24 shared papers)Ron Smits (11 shared papers)P. Meera Khan (19 shared papers)Menno F. Kielman (4 shared papers)Carli M.J. Tops (16 shared papers)C. van Leeuwen (6 shared papers)Hans F. A. Vasen (9 shared papers)Rob B. van der Luijt (5 shared papers)
Journals: Nucleic Acids Research (9 papers)The Journal of Immunology (5 papers)Human Genetics (4 papers)Genes Chromosomes and Cancer (3 papers)Gastroenterology (3 papers)
Partner nations: Netherlands United States Germany

In The Last Decade

Cor Breukel

58 papers receiving 3.4k citations

Cor Breukel's Hit Papers

align trajectories log scale

Mutations in the APC tumour suppressor gene cause chromosomal instability 2001 · 596 citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

2001 Nature Cell Biology

Peers

Countries citing papers authored by Cor Breukel

Since Specialization

Citations

This map shows the geographic impact of Cor Breukel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Cor Breukel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Cor Breukel more than expected).

Fields of papers citing papers by Cor Breukel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Cor Breukel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Cor Breukel. The network helps show where Cor Breukel may publish in the future.

Co-authors

The 25 scholars most cited alongside Cor Breukel, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Cor Breukel Line = papers co-authored together Cor Breukel links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 58 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Mutations in the APC tumour suppressor gene cause chromosomal instability Nature Cell Biology ·Riccardo Fodde, Jeroen Kuipers, Carla Rosenberg, Ron Smits, Menno F. Kielman, Johan H. van Es, Cor Breukel, Joop C. A. G. Wiegant Hit paper breakdown →	2001	596
2	A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors. Proceedings of the National Academy of Sciences ·Riccardo Fodde, Winfried Edelmann, Kan Yang, C. van Leeuwen, Christine Carlson, Beatrice Renault, Cor Breukel, P. Meera Khan +2 others	1994	449
3	Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catenin signaling Nature Genetics ·Menno F. Kielman, Maaret Rindapää, Nicole van Poppel, Cor Breukel, Sandra van Leeuwen, Makoto Mark Taketo, Ron Smits, Riccardo Fodde +2 others	2002	304
4	APC and Oncogenic KRAS Are Synergistic in Enhancing Wnt Signaling in Intestinal Tumor Formation and Progression Gastroenterology ·Klaus‐Peter Janssen, Paola Alberici, Hafida Fsihi, Cor Breukel, Patrick Franken, Christophe Rosty, Miguel Abal, Fatima El Marjou	2006	250
5	Molecular Analysis of Hereditary Nonpolyposis Colorectal Cancer in the United States: High Mutation Detection Rate among Clinically Selected Families and Characterization of an American Founder Genomic Deletion of the MSH2 Gene The American Journal of Human Genetics ·Anja Wagner, Alicia Barrows, Juul Wijnen, Heleen M. van der Klift, Patrick Franken, Paul Verkuijlen, Hidewaki Nakagawa, Marjan Geugien	2003	166
6	Hereditary desmoid disease due to a frameshift mutation at codon 1924 of the APC gene. PubMed ·Diana Eccles, Rob B. van der Luijt, Cor Breukel, H. Bullman, David J. Bunyan, Azetta Fisher, John C.K. Barber, John M. Primrose	1996	160
7	Germline mutations in the 3′ part of APC exon 15 do not result in truncated proteins and are associated with attenuated adenomatous polyposis coli Human Genetics ·Rob B. van der Luijt, P. Meera Khan, Hans F. A. Vasen, Cor Breukel, Carli M.J. Tops, Rodney John Scott, Riccardo Fodde	1996	137
8	Apc1638N: A mouse model for familial adenomatous polyposis–associated desmoid tumors and cutaneous cysts Gastroenterology ·Ron Smits, C. Willemien Menke‐van der Houven van Oordt, Arne Luz, CHRIS ZURCHER, Shantie Jagmohan–Changur, Cor Breukel, P. Meera Khan, Riccardo Fodde	1998	118
9	APC mutation in the alternatively spliced region of exon 9 associated with late onset familial adenomatous polyposis Human Genetics ·Rob B. van der Luijt, Hans F. A. Vasen, Carli M.J. Tops, Cor Breukel, Riccardo Fodde, P. Meera Khan	1995	104
10	The Inhibiting Fc Receptor for IgG, FcγRIIB, Is a Modifier of Autoimmune Susceptibility The Journal of Immunology ·Péter Boross, Victoria L. Arandhara, Javier Martín-Ramírez, Marie‐Laure Santiago‐Raber, Francesco Carlucci, Roelof Flierman, Jos van der Kaa, Cor Breukel	2011	97
11	SomaticApc mutations are selected upon their capacity to inactivate the ?-catenin downregulating activity Genes Chromosomes and Cancer ·Ron Smits, Nandy Hofland, Winfried Edelmann, Marjan Geugien, Shantie Jagmohan–Changur, Cristina M Albuquerque, Cor Breukel, Raju Kucherlapati	2000	78
12	Close linkage of a highly polymorphic marker (D5S37) to familial adenomatous polyposis (FAP) and confirmation of FAP localization on chromosome 5q21-q22 Human Genetics ·P. Meera Khan, Carli M.J. Tops, Cor Breukel, Juul Wijnen, Margot Oldenburg, Jetske van der Bos, Inge van Leeuwen‐Cornelisse, Hans F. A. Vasen	1988	75
13	A Targeted Constitutive Mutation in the Apc Tumor Suppressor Gene Underlies Mammary But Not Intestinal Tumorigenesis PLoS Genetics ·Patrick Franken, Lia Molenaar, Cor Breukel, Martin van der Valk, Ron Smits, Riccardo Fodde +1 other	2009	66
14	A new conditional Apc-mutant mouse model for colorectal cancer Carcinogenesis ·Els C. Robanus-Maandag, Pim J. Koelink, Cor Breukel, Daniela C. F. Salvatori, Shantie Jagmohan–Changur, Cathy A.J. Bosch, Hein W. Verspaget, Peter Devilee	2010	65
15	First FHM3 mouse model shows spontaneous cortical spreading depolarizations Annals of Clinical and Translational Neurology ·Nico A. Jansen, Anisa Dehghani, Margot M. L. Linssen, Cor Breukel, Else A. Tolner, Arn M. J. M. van den Maagdenberg	2019	59
16	A 10‐Mb paracentric inversion of chromosome arm 2p inactivates MSH2 and is responsible for hereditary nonpolyposis colorectal cancer in a North‐American kindred Genes Chromosomes and Cancer ·Anja Wagner, Heleen M. van der Klift, Patrick Franken, Juul Wijnen, Cor Breukel, Vladimir Bezrookove, Ron Smits, Yulia Kinarsky	2002	56
17	A dystrophic Duchenne mouse model for testing human antisense oligonucleotides PLoS ONE ·Marcel H. A. M. Veltrop, Laura Van de Vliet, Margriet Hulsker, Jill W. C. Claassens, Conny M. Brouwers, Cor Breukel, Jos van der Kaa, Margot M. L. Linssen	2018	52
18	A targeted mouse Brca1 mutation removing the last BRCT repeat results in apoptosis and embryonic lethality at the headfold stage Oncogene ·Peter Hohenstein, Menno F. Kielman, Cor Breukel, L. Michelle Bennett, Roger W. Wiseman, Paul Krimpenfort, Cees J. Cornelisse, Gert‐Jan B. van Ommen	2001	51
19	PRESYMPTOMATIC DIAGNOSIS OF FAMILIAL ADENOMATOUS POLYPOSIS BY BRIDGING DNA MARKERS The Lancet ·Carli M.J. Tops, Gerrit G. Griffioen, Hans F. A. Vasen, Cor Breukel, H.v d Klift, JT Wijnen, Inge S. J. van Leeuwen, F.C.A. den Hartog Jager	1989	50
20	E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice Gastroenterology ·Ron Smits, Patricia Ruíz, Salvador J. Diaz-Cano, Arne Luz, Shantie Jagmohan–Changur, Cor Breukel, Carmen Birchmeier, Walter Birchmeier	2000	49

About Cor Breukel

Cor Breukel is a scholar working on Pathology and Forensic Medicine, Molecular Biology, Rheumatology, Radiology, Nuclear Medicine and Imaging and Immunology, having authored 58 papers that have together received 3.6k indexed citations. Recurring topics across this work include Genetic factors in colorectal cancer (29 papers), Wnt/β-catenin signaling in development and cancer (5 papers), Monoclonal and Polyclonal Antibodies Research (5 papers), Biochemical and Molecular Research (4 papers), Systemic Lupus Erythematosus Research (3 papers), Cancer Immunotherapy and Biomarkers (2 papers), Migraine and Headache Studies (2 papers) and Genomic variations and chromosomal abnormalities (2 papers). The work is most often cited by research in Pathology and Forensic Medicine (1.3k citations), Oncology (432 citations), Molecular Biology (1.2k citations), Cell Biology (194 citations) and Cancer Research (156 citations). Cor Breukel has collaborated with scholars based in Netherlands, United States and Germany. Frequent co-authors include Riccardo Fodde, Ron Smits, P. Meera Khan, Menno F. Kielman, Carli M.J. Tops, C. van Leeuwen, Hans F. A. Vasen, Rob B. van der Luijt, Johan H. van Es and Hans C. Clevers. Their work appears in journals such as Nucleic Acids Research, The Journal of Immunology, Human Genetics, Genes Chromosomes and Cancer and Gastroenterology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Cor Breukel

Cor Breukel's Hit Papers

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