James Chen
Impact in
- Molecular Biology top 0.2%
- Hedgehog Signaling Pathway Studies
- Epigenetics and DNA Methylation
- Genomics and Chromatin Dynamics
- Developmental Biology and Gene Regulation
- Cell Biology top 0.5%
- Microtubule and mitosis dynamics
Papers in
-
- Hedgehog Signaling Pathway Studies 33
- Epigenetics and DNA Methylation 23
- Developmental Biology and Gene Regulation 13
- Advanced biosensing and bioanalysis techniques 12
- Cell Biology 24
- Microtubule and mitosis dynamics 10
- Zebrafish Biomedical Research Applications 8
- Co-authors
- Philip A. Beachy (7 shared papers)Jussi Taipale (4 shared papers)Michael K. Cooper (3 shared papers)Sibo Feng (3 shared papers)Hongtao Yu (2 shared papers)Surajit Sinha (6 shared papers)Stuart L. Schreiber (11 shared papers)Andrew W. Brauer (2 shared papers)
- Journals
- Nature Chemical Biology (10 papers)Proceedings of the National Academy of Sciences (7 papers)Journal of the American Chemical Society (5 papers)ACS Chemical Biology (5 papers)Development (4 papers)
- Partner nations
- United StatesCanadaUnited Kingdom
In The Last Decade
James Chen
220 papers receiving 14.4k citations
James Chen's Hit Papers
Peers
Comparison fields: 5 of 196
- Molecular Biology 10.1k
- Cell Biology 1.6k
- Oncology 2.0k
- Genetics 738
- Genetics 1.9k
Countries citing papers authored by James Chen
This map shows the geographic impact of James Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James Chen more than expected).
Fields of papers citing papers by James Chen
This network shows the impact of papers produced by James Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James Chen. The network helps show where James Chen may publish in the future.
Co-authors
The 25 scholars most cited alongside James Chen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.
All Works
Showing the 20 most-cited of 234 papers — load more, or switch the sort, to bring in the rest.
| # | Work | ||
|---|---|---|---|
| 1 | Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened Hit paper breakdown → | 2002 | 1240 |
| 2 | Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine Hit paper breakdown → | 2000 | 1108 |
| 3 | Structural basis for the binding of proline-rich peptides to SH3 domains Hit paper breakdown → | 1994 | 910 |
| 4 | Small molecule modulation of Smoothened activity Hit paper breakdown → | 2002 | 838 |
| 5 | Two Binding Orientations for Peptides to the Src SH3 Domain: Development of a General Model for SH3-Ligand Interactions Hit paper breakdown → | 1994 | 727 |
| 6 | Medulloblastoma Growth Inhibition by Hedgehog Pathway Blockade Hit paper breakdown → | 2002 | 663 |
| 7 | Organic wastewater treatment by a single-atom catalyst and electrolytically produced H2O2 Hit paper breakdown → | 2020 | 606 |
| 8 | Stromal response to Hedgehog signaling restrains pancreatic cancer progression Hit paper breakdown → | 2014 | 403 |
| 9 | 2005 | 319 | |
| 10 | 2012 | 301 | |
| 11 | 2012 | 290 | |
| 12 | 1986 | 279 | |
| 13 | 2009 | 262 | |
| 14 | 2009 | 253 | |
| 15 | 2004 | 229 | |
| 16 | 2006 | 207 | |
| 17 | 2007 | 202 | |
| 18 | 2006 | 195 | |
| 19 | 2016 | 190 | |
| 20 | 2017 | 180 |
About James Chen
James Chen is a scholar working on Molecular Biology, Cell Biology, Genetics, Electrical and Electronic Engineering and Materials Chemistry, having authored 234 papers that have together received 14.9k indexed citations. Recurring topics across this work include Hedgehog Signaling Pathway Studies (33 papers), Epigenetics and DNA Methylation (23 papers), Developmental Biology and Gene Regulation (13 papers), Advanced biosensing and bioanalysis techniques (12 papers), Microtubule and mitosis dynamics (10 papers), Photoreceptor and optogenetics research (10 papers), Photochromic and Fluorescence Chemistry (9 papers) and Zebrafish Biomedical Research Applications (8 papers). The work is most often cited by research in Molecular Biology (10.1k citations), Cell Biology (1.6k citations), Oncology (2.0k citations), Genetics (738 citations) and Genetics (1.9k citations). James Chen has collaborated with scholars based in United States, Canada and United Kingdom. Frequent co-authors include Philip A. Beachy, Jussi Taipale, Michael K. Cooper, Sibo Feng, Hongtao Yu, Surajit Sinha, Stuart L. Schreiber, Andrew W. Brauer, Tapan Maiti and Keith E. Young. Their work appears in journals such as Nature Chemical Biology, Proceedings of the National Academy of Sciences, Journal of the American Chemical Society, ACS Chemical Biology and Development.
Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.