James Chen

19.0k citations
227 papers · 14.2k · 8 hit papers · h-index 54

Impact in

    • Hedgehog Signaling Pathway Studies
    • Epigenetics and DNA Methylation
    • Genomics and Chromatin Dynamics
    • Developmental Biology and Gene Regulation
  • Cell Biology top 0.5%
    • Microtubule and mitosis dynamics

Papers in

    • Hedgehog Signaling Pathway Studies 32
    • Epigenetics and DNA Methylation 23
    • Developmental Biology and Gene Regulation 13
    • Advanced biosensing and bioanalysis techniques 12
    • Microtubule and mitosis dynamics 10
    • Zebrafish Biomedical Research Applications 8

James Chen

211 papers receiving 13.9k citations

James Chen's Hit Papers

Organic wastewater treatment by a single-atom catalyst and electrolytically produced H2O2 2020 · 572 citations
5720+10+21Years since publication4008001.2k

Peers

James Chen
Comparison fields: 5 of 197
  • Molecular Biology 10.1k
  • Cell Biology 1.5k
  • Oncology 2.1k
  • Genetics 757
  • Genetics 1.9k
Replace Nicholas D. Socci with:
Nicholas D. Socci United States
David M. Berman United States
Anne E. Carpenter United States
Ulf Landegren Sweden
Andre Levchenko United States
William G. Richards United States
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David Givol Israel
Julio E. Celis Denmark
James Chen relative to Nicholas D. Socci United States Nicholas D. Socci's profile →
Citations per field
00.5×1.5×
Nicholas D. Socci · 1×
Citations per year

Countries citing papers authored by James Chen

Since Specialization
Citations

This map shows the geographic impact of James Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James Chen more than expected).

Fields of papers citing papers by James Chen

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James Chen. The network helps show where James Chen may publish in the future.

Co-authors

The 25 scholars most cited alongside James Chen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with James Chen Line = papers co-authored together James Chen links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 227 papers — load more, or switch the sort, to bring in the rest.

#Work
1
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
Hit paper breakdown →
20021201
2
Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
Hit paper breakdown →
20001071
3
Structural basis for the binding of proline-rich peptides to SH3 domains
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1994880
4
Small molecule modulation of Smoothened activity
Hit paper breakdown →
2002817
5
Two Binding Orientations for Peptides to the Src SH3 Domain: Development of a General Model for SH3-Ligand Interactions
Hit paper breakdown →
1994715
6
Medulloblastoma Growth Inhibition by Hedgehog Pathway Blockade
Hit paper breakdown →
2002632
7
Organic wastewater treatment by a single-atom catalyst and electrolytically produced H2O2
Hit paper breakdown →
2020572
8
Stromal response to Hedgehog signaling restrains pancreatic cancer progression
Hit paper breakdown →
2014386
9 2005309
10 2012293
11 2012280
12 1986254
13 2009253
14 2009241
15 2004221
16 2007192
17 2006188
18 2006184
19 2016183
20 2017176

About James Chen

James Chen is a scholar working on Molecular Biology, Cell Biology, Genetics, Oncology and Electrical and Electronic Engineering, having authored 227 papers that have together received 14.2k indexed citations. Recurring topics across this work include Hedgehog Signaling Pathway Studies (32 papers), Epigenetics and DNA Methylation (23 papers), Developmental Biology and Gene Regulation (13 papers), Advanced biosensing and bioanalysis techniques (12 papers), Microtubule and mitosis dynamics (10 papers), Photoreceptor and optogenetics research (10 papers), Photochromic and Fluorescence Chemistry (9 papers) and Zebrafish Biomedical Research Applications (8 papers). The work is most often cited by research in Molecular Biology (10.1k citations), Cell Biology (1.5k citations), Oncology (2.1k citations), Genetics (757 citations) and Genetics (1.9k citations). James Chen has collaborated with scholars based in United States, Canada and China. Frequent co-authors include Philip A. Beachy, Jussi Taipale, Michael K. Cooper, Sibo Feng, Hongtao Yu, Surajit Sinha, Stuart L. Schreiber, Andrew W. Brauer, Keith E. Young and Tapan Maiti. Their work appears in journals such as Nature Chemical Biology, Proceedings of the National Academy of Sciences, Journal of the American Chemical Society, ACS Chemical Biology and The Journal of Cell Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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